Datasets:

JerMa88
/

BMC_Womens_Health_Peer_Reviews

title stringlengths 32 37	abstract stringclasses 1 value	full_text stringlengths 88 56k	review stringlengths 88 56k	source stringclasses 1 value	review_src stringlengths 37 42	criteria_count dict	dimension_scores dict	overall_score float64 0 7	conversations listlengths 2 2	year int64 2k 2.03k
Review for 10.1186/s12905-025-03650-1	Reviewed - bmc_womens_health	Title: Risk Factors for Postoperative Hypoproteinemia in Ovarian Cancer: A Predictive Nomogram Version: 1 Date: 09 Feb 2025 Reviewer's report: The authors aim to identify risk factors for postoperative hypoproteinemia after radical ovarian cancer surgery. They found high preoperative CRP level, low ALB level, excessive intraoperative net fluid gain, weight loss >5% in the month prior to surgery, and concomitant gastrointestinal surgery are independent risk factors for postoperative hypoalbuminemia in these patients. A nomogram prediction model was developed with reasonable accuracy and prediction value. This was a well done study addressing the need to recognize the high incidence of postoperative hypoproteinemia which are associated with high morbidity. I have a few questions: 1. Sincere there was a difference in the length of surgery (LOS)between the two groups, why was LOS not part of the multivariate analysis? Obviously as the authors stated, longer surgery requires more fluids, and fluids in itself was associated with hypoproteinemia. 2. Since all surgeries were performed by the same team, did longer surgery indicate higher grade of cancer? 3. How many patients in each group received blood transfusion? Were the hemoglobin levels different between the two groups? Overall, I think it is a good paper to address the awareness of postoperative hypoproteinemia and help explore treatment aimed at reduced morbidity and mortality. I took the liberty to edit the manuscript, mostly to make it more succint. Weike Tao, MD	Title: Risk Factors for Postoperative Hypoproteinemia in Ovarian Cancer: A Predictive Nomogram Version: 1 Date: 09 Feb 2025 Reviewer's report: The authors aim to identify risk factors for postoperative hypoproteinemia after radical ovarian cancer surgery. They found high preoperative CRP level, low ALB level, excessive intraoperative net fluid gain, weight loss >5% in the month prior to surgery, and concomitant gastrointestinal surgery are independent risk factors for postoperative hypoalbuminemia in these patients. A nomogram prediction model was developed with reasonable accuracy and prediction value. This was a well done study addressing the need to recognize the high incidence of postoperative hypoproteinemia which are associated with high morbidity. I have a few questions: 1. Sincere there was a difference in the length of surgery (LOS)between the two groups, why was LOS not part of the multivariate analysis? Obviously as the authors stated, longer surgery requires more fluids, and fluids in itself was associated with hypoproteinemia. 2. Since all surgeries were performed by the same team, did longer surgery indicate higher grade of cancer? 3. How many patients in each group received blood transfusion? Were the hemoglobin levels different between the two groups? Overall, I think it is a good paper to address the awareness of postoperative hypoproteinemia and help explore treatment aimed at reduced morbidity and mortality. I took the liberty to edit the manuscript, mostly to make it more succint. Weike Tao, MD	BMC	12905_2025_3650_ReviewerReport_V1_R2.pdf	{ "criticism": 0, "example": 0, "importance_and_relevance": 2, "materials_and_methods": 7, "praise": 3, "presentation_and_reporting": 0, "results_and_discussion": 0, "suggestion_and_solution": 1, "total": 15 }	{ "criticism": 0, "example": 0, "importance_and_relevance": 0.13333333333333333, "materials_and_methods": 0.4666666666666667, "praise": 0.2, "presentation_and_reporting": 0, "results_and_discussion": 0, "suggestion_and_solution": 0.06666666666666667 }	0.866667	[ { "content": "Please review this paper.", "role": "user" }, { "content": "Title: Risk Factors for Postoperative Hypoproteinemia in Ovarian Cancer: A Predictive\nNomogram\nVersion: 1 Date: 09 Feb 2025\nReviewer's report:\nThe authors aim to identify risk factors for postoperative hypoproteinemia after radical\novarian cancer surgery. They found high preoperative CRP level, low ALB level, excessive\nintraoperative net fluid gain, weight loss >5% in the month prior to surgery, and concomitant\ngastrointestinal surgery are independent risk factors for postoperative hypoalbuminemia in these\npatients. A nomogram prediction model was developed with reasonable accuracy and prediction\nvalue. This was a well done study addressing the need to recognize the high incidence of\npostoperative hypoproteinemia which are associated with high morbidity.\nI have a few questions:\n1. Sincere there was a difference in the length of surgery (LOS)between the two groups, why\nwas LOS not part of the multivariate analysis? Obviously as the authors stated, longer surgery\nrequires more fluids, and fluids in itself was associated with hypoproteinemia.\n2. Since all surgeries were performed by the same team, did longer surgery indicate higher grade\nof cancer?\n3. How many patients in each group received blood transfusion? Were the hemoglobin levels\ndifferent between the two groups?\nOverall, I think it is a good paper to address the awareness of postoperative hypoproteinemia\nand help explore treatment aimed at reduced morbidity and mortality.\nI took the liberty to edit the manuscript, mostly to make it more succint.\nWeike Tao, MD", "role": "assistant" } ]	2,025
Review for 10.1186/s12905-025-03650-1	Reviewed - bmc_womens_health	Title: Risk Factors for Postoperative Hypoproteinemia in Ovarian Cancer: A Predictive Nomogram Version: 1 Date: 14 Feb 2025 Reviewer: Kyung Jin Eoh Reviewer's report: The manuscript presents important findings and a predictive nomogram that could be of significant clinical value. Below are some minor revisions that could further enhance the clarity and accuracy of the paper. 1. In the abstract and throughout the manuscript, the terms "hypoproteinemia" and "hypoalbuminemia" are used interchangeably. Since the study focuses on albumin levels, it would be preferable to use "hypoalbuminemia" consistently to avoid potential confusion. 2. There are minor spacing inconsistencies in some sections (e.g., in the keywords: "Keywords:Ovarian cancer,Radical surgery,Hypoproteinemia,Risk factors,Nomogram"). A quick proofreading check to ensure proper spacing and uniform formatting would improve readability. 3. In the results section, cut-off values for CRP (6.69 mg/L), ALB (43.35 g/L), and net fluid balance/weight (40.71 mL/kg) were used. It would strengthen the validity of the study if a brief explanation is provided on how these cut-off points were determined (e.g., ROC curve optimization, clinical relevance, or prior literature).	Title: Risk Factors for Postoperative Hypoproteinemia in Ovarian Cancer: A Predictive Nomogram Version: 1 Date: 14 Feb 2025 Reviewer: Kyung Jin Eoh Reviewer's report: The manuscript presents important findings and a predictive nomogram that could be of significant clinical value. Below are some minor revisions that could further enhance the clarity and accuracy of the paper. 1. In the abstract and throughout the manuscript, the terms "hypoproteinemia" and "hypoalbuminemia" are used interchangeably. Since the study focuses on albumin levels, it would be preferable to use "hypoalbuminemia" consistently to avoid potential confusion. 2. There are minor spacing inconsistencies in some sections (e.g., in the keywords: "Keywords:Ovarian cancer,Radical surgery,Hypoproteinemia,Risk factors,Nomogram"). A quick proofreading check to ensure proper spacing and uniform formatting would improve readability. 3. In the results section, cut-off values for CRP (6.69 mg/L), ALB (43.35 g/L), and net fluid balance/weight (40.71 mL/kg) were used. It would strengthen the validity of the study if a brief explanation is provided on how these cut-off points were determined (e.g., ROC curve optimization, clinical relevance, or prior literature).	BMC	12905_2025_3650_ReviewerReport_V1_R1.pdf	{ "criticism": 1, "example": 1, "importance_and_relevance": 1, "materials_and_methods": 2, "praise": 1, "presentation_and_reporting": 4, "results_and_discussion": 2, "suggestion_and_solution": 4, "total": 11 }	{ "criticism": 0.09090909090909091, "example": 0.09090909090909091, "importance_and_relevance": 0.09090909090909091, "materials_and_methods": 0.18181818181818182, "praise": 0.09090909090909091, "presentation_and_reporting": 0.36363636363636365, "results_and_discussion": 0.18181818181818182, "suggestion_and_solution": 0.36363636363636365 }	1.454545	[ { "content": "Please review this paper.", "role": "user" }, { "content": "Title: Risk Factors for Postoperative Hypoproteinemia in Ovarian Cancer: A Predictive\nNomogram\nVersion: 1 Date: 14 Feb 2025\nReviewer: Kyung Jin Eoh\nReviewer's report:\nThe manuscript presents important findings and a predictive nomogram that could be of\nsignificant clinical value. Below are some minor revisions that could further enhance the clarity\nand accuracy of the paper.\n1. In the abstract and throughout the manuscript, the terms \"hypoproteinemia\" and\n\"hypoalbuminemia\" are used interchangeably. Since the study focuses on albumin levels, it\nwould be preferable to use \"hypoalbuminemia\" consistently to avoid potential confusion.\n2. There are minor spacing inconsistencies in some sections (e.g., in the keywords:\n\"Keywords:Ovarian cancer,Radical surgery,Hypoproteinemia,Risk factors,Nomogram\"). A\nquick proofreading check to ensure proper spacing and uniform formatting would improve\nreadability.\n3. In the results section, cut-off values for CRP (6.69 mg/L), ALB (43.35 g/L), and net fluid\nbalance/weight (40.71 mL/kg) were used. It would strengthen the validity of the study if a\nbrief explanation is provided on how these cut-off points were determined (e.g., ROC curve\noptimization, clinical relevance, or prior literature).", "role": "assistant" } ]	2,025
Review for 10.1186/s12905-025-03650-1	Reviewed - bmc_womens_health	Title: Risk Factors for Postoperative Hypoproteinemia in Ovarian Cancer: A Predictive Nomogram Version: 2 Date: 01 Mar 2025 Reviewer: Kyung Jin Eoh Reviewer's report: The authors have improved the manuscript by sufficiently incorporating the reviewer's feedback.	Title: Risk Factors for Postoperative Hypoproteinemia in Ovarian Cancer: A Predictive Nomogram Version: 2 Date: 01 Mar 2025 Reviewer: Kyung Jin Eoh Reviewer's report: The authors have improved the manuscript by sufficiently incorporating the reviewer's feedback.	BMC	12905_2025_3650_ReviewerReport_V2_R1.pdf	{ "criticism": 0, "example": 0, "importance_and_relevance": 0, "materials_and_methods": 0, "praise": 1, "presentation_and_reporting": 0, "results_and_discussion": 0, "suggestion_and_solution": 0, "total": 1 }	{ "criticism": 0, "example": 0, "importance_and_relevance": 0, "materials_and_methods": 0, "praise": 1, "presentation_and_reporting": 0, "results_and_discussion": 0, "suggestion_and_solution": 0 }	1	[ { "content": "Please review this paper.", "role": "user" }, { "content": "Title: Risk Factors for Postoperative Hypoproteinemia in Ovarian Cancer: A Predictive\nNomogram\nVersion: 2 Date: 01 Mar 2025\nReviewer: Kyung Jin Eoh\nReviewer's report:\nThe authors have improved the manuscript by sufficiently incorporating the reviewer's feedback.", "role": "assistant" } ]	2,025
Review for 10.1186/s12905-025-03650-1	Reviewed - bmc_womens_health	Title: Risk Factors for Postoperative Hypoproteinemia in Ovarian Cancer: A Predictive Nomogram Version: 2 Date: 02 Mar 2025 Reviewer's report: The authors have adequately address the questions I had. There are still some typos which I editied. The manuscript is acceptable for publication.	Title: Risk Factors for Postoperative Hypoproteinemia in Ovarian Cancer: A Predictive Nomogram Version: 2 Date: 02 Mar 2025 Reviewer's report: The authors have adequately address the questions I had. There are still some typos which I editied. The manuscript is acceptable for publication.	BMC	12905_2025_3650_ReviewerReport_V2_R2.pdf	{ "criticism": 1, "example": 0, "importance_and_relevance": 0, "materials_and_methods": 0, "praise": 1, "presentation_and_reporting": 1, "results_and_discussion": 0, "suggestion_and_solution": 0, "total": 3 }	{ "criticism": 0.3333333333333333, "example": 0, "importance_and_relevance": 0, "materials_and_methods": 0, "praise": 0.3333333333333333, "presentation_and_reporting": 0.3333333333333333, "results_and_discussion": 0, "suggestion_and_solution": 0 }	1	[ { "content": "Please review this paper.", "role": "user" }, { "content": "Title: Risk Factors for Postoperative Hypoproteinemia in Ovarian Cancer: A Predictive\nNomogram\nVersion: 2 Date: 02 Mar 2025\nReviewer's report:\nThe authors have adequately address the questions I had. There are still some typos which I\neditied. The manuscript is acceptable for publication.", "role": "assistant" } ]	2,025
Review for 10.1186/s12905-025-03622-5	Reviewed - bmc_womens_health	Title: Serum lactate dehydrogenase level in preeclampsia and its correlation with disease severity, maternal and perinatal outcomes Version: 1 Date: 04 Jun 2024 Reviewer: Süleyman Cemil O#lak Reviewer's report: I consider that this study does not offer new information or significant findings that enhance our knowledge regarding the correlation between serum lactate dehydrogenase level with disease severity, and maternal and perinatal outcomes in preeclampsia. Lots of similar studies exist in the literature. Also, a recent comprehensive review concluded similar findings (Deeksha HS, Pajai S, Reddy Eleti M, Navalihiremath VU. A Comprehensive Review on Serum Lactate Dehydrogenase (LDH) and Uric Acid in Preeclampsia: Implications for Maternal Health and Disease Severity. Cureus. 2024;16(3):e56928).	Title: Serum lactate dehydrogenase level in preeclampsia and its correlation with disease severity, maternal and perinatal outcomes Version: 1 Date: 04 Jun 2024 Reviewer: Süleyman Cemil O#lak Reviewer's report: I consider that this study does not offer new information or significant findings that enhance our knowledge regarding the correlation between serum lactate dehydrogenase level with disease severity, and maternal and perinatal outcomes in preeclampsia. Lots of similar studies exist in the literature. Also, a recent comprehensive review concluded similar findings (Deeksha HS, Pajai S, Reddy Eleti M, Navalihiremath VU. A Comprehensive Review on Serum Lactate Dehydrogenase (LDH) and Uric Acid in Preeclampsia: Implications for Maternal Health and Disease Severity. Cureus. 2024;16(3):e56928).	BMC	12905_2025_3622_ReviewerReport_V1_R3.pdf	{ "criticism": 1, "example": 0, "importance_and_relevance": 1, "materials_and_methods": 0, "praise": 0, "presentation_and_reporting": 0, "results_and_discussion": 2, "suggestion_and_solution": 0, "total": 6 }	{ "criticism": 0.16666666666666666, "example": 0, "importance_and_relevance": 0.16666666666666666, "materials_and_methods": 0, "praise": 0, "presentation_and_reporting": 0, "results_and_discussion": 0.3333333333333333, "suggestion_and_solution": 0 }	0.666667	[ { "content": "Please review this paper.", "role": "user" }, { "content": "Title: Serum lactate dehydrogenase level in preeclampsia and its correlation with disease\nseverity, maternal and perinatal outcomes\nVersion: 1 Date: 04 Jun 2024\nReviewer: Süleyman Cemil O#lak\nReviewer's report:\nI consider that this study does not offer new information or significant findings that enhance our\nknowledge regarding the correlation between serum lactate dehydrogenase level with disease\nseverity, and maternal and perinatal outcomes in preeclampsia. Lots of similar studies exist\nin the literature. Also, a recent comprehensive review concluded similar findings (Deeksha\nHS, Pajai S, Reddy Eleti M, Navalihiremath VU. A Comprehensive Review on Serum Lactate\nDehydrogenase (LDH) and Uric Acid in Preeclampsia: Implications for Maternal Health and\nDisease Severity. Cureus. 2024;16(3):e56928).", "role": "assistant" } ]	2,025
Review for 10.1186/s12905-025-03622-5	Reviewed - bmc_womens_health	Title: Serum lactate dehydrogenase level in preeclampsia and its correlation with disease severity, maternal and perinatal outcomes Version: 1 Date: 04 Jun 2024 Reviewer's report: Nasir et al. have aimed to evaluate the levels of lactate dehydrogenase (LDH) in pregnant women complicated with preeclampsia and its correlation with the severity of the disease and the maternal and perinatal outcomes. Moreover, they emphasized that LDH can be a valuable biomarker for predicting the severity of preeclampsia. The study is orginal, well prepared and discused. In my opinion this paper has a potential to make a positive contribution to the co- existing literature. I have only some minor recommendations for the authors: 1- I think that preeclampsia may cause neonatal and maternal morbidity due to its severity. Uric acid and the platelet-lymphocyte ratio (PLR), which can be easily calculated clinically may predict adverse neonatal outcomes. The study mentioned below may contribute to this article. “Yaki#tiran B, Tanaçan A, Altinbo#a O, et al. Role of derived neutrophil-to-lymphocyte ratio, uric acid-to-creatinine ratio and Delta neutrophil index for predicting neonatal outcomes in pregnancies with preeclampsia. J Obstet Gynaecol. 2022;42(6):1835-1840. doi:10.1080/01443615.2022.2040968”	Title: Serum lactate dehydrogenase level in preeclampsia and its correlation with disease severity, maternal and perinatal outcomes Version: 1 Date: 04 Jun 2024 Reviewer's report: Nasir et al. have aimed to evaluate the levels of lactate dehydrogenase (LDH) in pregnant women complicated with preeclampsia and its correlation with the severity of the disease and the maternal and perinatal outcomes. Moreover, they emphasized that LDH can be a valuable biomarker for predicting the severity of preeclampsia. The study is orginal, well prepared and discused. In my opinion this paper has a potential to make a positive contribution to the co- existing literature. I have only some minor recommendations for the authors: 1- I think that preeclampsia may cause neonatal and maternal morbidity due to its severity. Uric acid and the platelet-lymphocyte ratio (PLR), which can be easily calculated clinically may predict adverse neonatal outcomes. The study mentioned below may contribute to this article. “Yaki#tiran B, Tanaçan A, Altinbo#a O, et al. Role of derived neutrophil-to-lymphocyte ratio, uric acid-to-creatinine ratio and Delta neutrophil index for predicting neonatal outcomes in pregnancies with preeclampsia. J Obstet Gynaecol. 2022;42(6):1835-1840. doi:10.1080/01443615.2022.2040968”	BMC	12905_2025_3622_ReviewerReport_V1_R1.pdf	{ "criticism": 0, "example": 1, "importance_and_relevance": 1, "materials_and_methods": 4, "praise": 3, "presentation_and_reporting": 1, "results_and_discussion": 1, "suggestion_and_solution": 1, "total": 12 }	{ "criticism": 0, "example": 0.08333333333333333, "importance_and_relevance": 0.08333333333333333, "materials_and_methods": 0.3333333333333333, "praise": 0.25, "presentation_and_reporting": 0.08333333333333333, "results_and_discussion": 0.08333333333333333, "suggestion_and_solution": 0.08333333333333333 }	1	[ { "content": "Please review this paper.", "role": "user" }, { "content": "Title: Serum lactate dehydrogenase level in preeclampsia and its correlation with disease\nseverity, maternal and perinatal outcomes\nVersion: 1 Date: 04 Jun 2024\nReviewer's report:\nNasir et al. have aimed to evaluate the levels of lactate dehydrogenase (LDH) in pregnant\nwomen complicated with preeclampsia and its correlation with the severity of the disease and\nthe maternal and perinatal outcomes. Moreover, they emphasized that LDH can be a valuable\nbiomarker for predicting the severity of preeclampsia. The study is orginal, well prepared and\ndiscused. In my opinion this paper has a potential to make a positive contribution to the co-\nexisting literature. I have only some minor recommendations for the authors:\n1- I think that preeclampsia may cause neonatal and maternal morbidity due to its severity.\nUric acid and the platelet-lymphocyte ratio (PLR), which can be easily calculated clinically may\npredict adverse neonatal outcomes. The study mentioned below may contribute to this article.\n“Yaki#tiran B, Tanaçan A, Altinbo#a O, et al. Role of derived neutrophil-to-lymphocyte\nratio, uric acid-to-creatinine ratio and Delta neutrophil index for predicting neonatal\noutcomes in pregnancies with preeclampsia. J Obstet Gynaecol. 2022;42(6):1835-1840.\ndoi:10.1080/01443615.2022.2040968”", "role": "assistant" } ]	2,025
Review for 10.1186/s12905-025-03622-5	Reviewed - bmc_womens_health	Title: Serum lactate dehydrogenase level in preeclampsia and its correlation with disease severity, maternal and perinatal outcomes Version: 1 Date: 09 Jun 2024 Reviewer: Almagul Kurmanova Reviewer's report: The study is devoted to an urgent problem - early prediction of severe preeclampsia and adverse obstetric and perinatal outcomes. The introduction should justify the choice of LDH as a potential marker of severe preeclampsia. In materials and methods - Normal levels of LDH in the blood can vary depending on the lab, what LDH level was considered elevated?	Title: Serum lactate dehydrogenase level in preeclampsia and its correlation with disease severity, maternal and perinatal outcomes Version: 1 Date: 09 Jun 2024 Reviewer: Almagul Kurmanova Reviewer's report: The study is devoted to an urgent problem - early prediction of severe preeclampsia and adverse obstetric and perinatal outcomes. The introduction should justify the choice of LDH as a potential marker of severe preeclampsia. In materials and methods - Normal levels of LDH in the blood can vary depending on the lab, what LDH level was considered elevated?	BMC	12905_2025_3622_ReviewerReport_V1_R4.pdf	{ "criticism": 0, "example": 0, "importance_and_relevance": 0, "materials_and_methods": 1, "praise": 1, "presentation_and_reporting": 0, "results_and_discussion": 0, "suggestion_and_solution": 1, "total": 3 }	{ "criticism": 0, "example": 0, "importance_and_relevance": 0, "materials_and_methods": 0.3333333333333333, "praise": 0.3333333333333333, "presentation_and_reporting": 0, "results_and_discussion": 0, "suggestion_and_solution": 0.3333333333333333 }	1	[ { "content": "Please review this paper.", "role": "user" }, { "content": "Title: Serum lactate dehydrogenase level in preeclampsia and its correlation with disease\nseverity, maternal and perinatal outcomes\nVersion: 1 Date: 09 Jun 2024\nReviewer: Almagul Kurmanova\nReviewer's report:\nThe study is devoted to an urgent problem - early prediction of severe preeclampsia and adverse\nobstetric and perinatal outcomes.\nThe introduction should justify the choice of LDH as a potential marker of severe preeclampsia.\nIn materials and methods - Normal levels of LDH in the blood can vary depending on the lab,\nwhat LDH level was considered elevated?", "role": "assistant" } ]	2,025
Review for 10.1186/s12905-025-03622-5	Reviewed - bmc_womens_health	Title: Serum lactate dehydrogenase level in preeclampsia and its correlation with disease severity, maternal and perinatal outcomes Version: 2 Date: 24 Jun 2024 Reviewer: Almagul Kurmanova Reviewer's report: Page 4 line 122, Please put a space between words, yellow highlights	Title: Serum lactate dehydrogenase level in preeclampsia and its correlation with disease severity, maternal and perinatal outcomes Version: 2 Date: 24 Jun 2024 Reviewer: Almagul Kurmanova Reviewer's report: Page 4 line 122, Please put a space between words, yellow highlights	BMC	12905_2025_3622_ReviewerReport_V2_R4.pdf	{ "criticism": 0, "example": 1, "importance_and_relevance": 0, "materials_and_methods": 0, "praise": 0, "presentation_and_reporting": 1, "results_and_discussion": 0, "suggestion_and_solution": 1, "total": 1 }	{ "criticism": 0, "example": 1, "importance_and_relevance": 0, "materials_and_methods": 0, "praise": 0, "presentation_and_reporting": 1, "results_and_discussion": 0, "suggestion_and_solution": 1 }	3	[ { "content": "Please review this paper.", "role": "user" }, { "content": "Title: Serum lactate dehydrogenase level in preeclampsia and its correlation with disease\nseverity, maternal and perinatal outcomes\nVersion: 2 Date: 24 Jun 2024\nReviewer: Almagul Kurmanova\nReviewer's report:\nPage 4 line 122, Please put a space between words, yellow\nhighlights", "role": "assistant" } ]	2,025
Review for 10.1186/s12905-025-03622-5	Reviewed - bmc_womens_health	Title: Serum lactate dehydrogenase level in preeclampsia and its correlation with disease severity, maternal and perinatal outcomes Version: 2 Date: 24 Jun 2024 Reviewer's report: The authors have made the necessary changes to the article can be published in its present form. Thank you.	Title: Serum lactate dehydrogenase level in preeclampsia and its correlation with disease severity, maternal and perinatal outcomes Version: 2 Date: 24 Jun 2024 Reviewer's report: The authors have made the necessary changes to the article can be published in its present form. Thank you.	BMC	12905_2025_3622_ReviewerReport_V2_R1.pdf	{ "criticism": 0, "example": 0, "importance_and_relevance": 0, "materials_and_methods": 0, "praise": 0, "presentation_and_reporting": 0, "results_and_discussion": 0, "suggestion_and_solution": 1, "total": 2 }	{ "criticism": 0, "example": 0, "importance_and_relevance": 0, "materials_and_methods": 0, "praise": 0, "presentation_and_reporting": 0, "results_and_discussion": 0, "suggestion_and_solution": 0.5 }	0.5	[ { "content": "Please review this paper.", "role": "user" }, { "content": "Title: Serum lactate dehydrogenase level in preeclampsia and its correlation with disease\nseverity, maternal and perinatal outcomes\nVersion: 2 Date: 24 Jun 2024\nReviewer's report:\nThe authors have made the necessary changes to the article can be published in its present form.\nThank you.", "role": "assistant" } ]	2,025
Review for 10.1186/s12905-025-03622-5	Reviewed - bmc_womens_health	Title: Serum lactate dehydrogenase level in preeclampsia and its correlation with disease severity, maternal and perinatal outcomes Version: 2 Date: 26 Jun 2024 Reviewer's report: 1.There is a relatively large literatüre investigating serum lactate dehydrogenase level in preeclampsia This literatüre was underutilized here. It needs to be reviewed more fully to make a stronger case for the importance of the study (in the Introduction and Discussion).	Title: Serum lactate dehydrogenase level in preeclampsia and its correlation with disease severity, maternal and perinatal outcomes Version: 2 Date: 26 Jun 2024 Reviewer's report: 1.There is a relatively large literatüre investigating serum lactate dehydrogenase level in preeclampsia This literatüre was underutilized here. It needs to be reviewed more fully to make a stronger case for the importance of the study (in the Introduction and Discussion).	BMC	12905_2025_3622_ReviewerReport_V2_R2.pdf	{ "criticism": 1, "example": 0, "importance_and_relevance": 1, "materials_and_methods": 0, "praise": 0, "presentation_and_reporting": 0, "results_and_discussion": 1, "suggestion_and_solution": 1, "total": 2 }	{ "criticism": 0.5, "example": 0, "importance_and_relevance": 0.5, "materials_and_methods": 0, "praise": 0, "presentation_and_reporting": 0, "results_and_discussion": 0.5, "suggestion_and_solution": 0.5 }	2	[ { "content": "Please review this paper.", "role": "user" }, { "content": "Title: Serum lactate dehydrogenase level in preeclampsia and its correlation with disease\nseverity, maternal and perinatal outcomes\nVersion: 2 Date: 26 Jun 2024\nReviewer's report:\n1.There is a relatively large literatüre investigating serum lactate dehydrogenase level in\npreeclampsia This literatüre was underutilized here. It needs to be reviewed more fully to make\na stronger case for the importance of the study (in the Introduction and Discussion).", "role": "assistant" } ]	2,025
Review for 10.1186/s12905-025-03622-5	Reviewed - bmc_womens_health	Title: Serum lactate dehydrogenase level in preeclampsia and its correlation with disease severity, maternal and perinatal outcomes Version: 2 Date: 29 Jun 2024 Reviewer's report: Hi, I found the study ineffective because conducting tests in the third trimester does not change the disease outcome. Additionally, factors such as age and BMI, which are already known risk factors for pre-eclampsia, introduce significant confounding variables. The study would have been more valuable if conducted before the 20th week of gestation.	Title: Serum lactate dehydrogenase level in preeclampsia and its correlation with disease severity, maternal and perinatal outcomes Version: 2 Date: 29 Jun 2024 Reviewer's report: Hi, I found the study ineffective because conducting tests in the third trimester does not change the disease outcome. Additionally, factors such as age and BMI, which are already known risk factors for pre-eclampsia, introduce significant confounding variables. The study would have been more valuable if conducted before the 20th week of gestation.	BMC	12905_2025_3622_ReviewerReport_V2_R7.pdf	{ "criticism": 1, "example": 0, "importance_and_relevance": 0, "materials_and_methods": 2, "praise": 0, "presentation_and_reporting": 0, "results_and_discussion": 0, "suggestion_and_solution": 1, "total": 3 }	{ "criticism": 0.3333333333333333, "example": 0, "importance_and_relevance": 0, "materials_and_methods": 0.6666666666666666, "praise": 0, "presentation_and_reporting": 0, "results_and_discussion": 0, "suggestion_and_solution": 0.3333333333333333 }	1.333333	[ { "content": "Please review this paper.", "role": "user" }, { "content": "Title: Serum lactate dehydrogenase level in preeclampsia and its correlation with disease\nseverity, maternal and perinatal outcomes\nVersion: 2 Date: 29 Jun 2024\nReviewer's report:\nHi,\nI found the study ineffective because conducting tests in the third trimester does not change\nthe disease outcome. Additionally, factors such as age and BMI, which are already known risk\nfactors for pre-eclampsia, introduce significant confounding variables. The study would have\nbeen more valuable if conducted before the 20th week of gestation.", "role": "assistant" } ]	2,025
Review for 10.1186/s12905-025-03622-5	Reviewed - bmc_womens_health	Title: Serum lactate dehydrogenase level in preeclampsia and its correlation with disease severity, maternal and perinatal outcomes Version: 2 Date: 01 Jul 2024 Reviewer's report: 1. lines 36 to 39 are out of place. We should first mention that there are predictors of adverse maternal and perinatal outcome in preeclampsia cases and so on ................... 2. Lines 46 to 47 - erroneously written 3. Lines 81 to 82 - There is no criteria for mild preeclampsia if BP is equal to or more than 160/110. We need to repeat BP after 15 minutes and then label 4. Figure 1 : shows maternal complications in which study group ? 5. There is difference in mean levels of LDH given in study group in Table 3 and 4 6. Please if you can specify when the sample for LDH was taken - at time of induction in study or at time of IOL, early labour or elective CS. A patient presenting at 28 weeks with mild preeclampsia, may develop preeclampsia in coming weeks and be having high LDH which we may not have evaluated	Title: Serum lactate dehydrogenase level in preeclampsia and its correlation with disease severity, maternal and perinatal outcomes Version: 2 Date: 01 Jul 2024 Reviewer's report: 1. lines 36 to 39 are out of place. We should first mention that there are predictors of adverse maternal and perinatal outcome in preeclampsia cases and so on ................... 2. Lines 46 to 47 - erroneously written 3. Lines 81 to 82 - There is no criteria for mild preeclampsia if BP is equal to or more than 160/110. We need to repeat BP after 15 minutes and then label 4. Figure 1 : shows maternal complications in which study group ? 5. There is difference in mean levels of LDH given in study group in Table 3 and 4 6. Please if you can specify when the sample for LDH was taken - at time of induction in study or at time of IOL, early labour or elective CS. A patient presenting at 28 weeks with mild preeclampsia, may develop preeclampsia in coming weeks and be having high LDH which we may not have evaluated	BMC	12905_2025_3622_ReviewerReport_V2_R5.pdf	{ "criticism": 2, "example": 4, "importance_and_relevance": 0, "materials_and_methods": 5, "praise": 0, "presentation_and_reporting": 3, "results_and_discussion": 0, "suggestion_and_solution": 3, "total": 10 }	{ "criticism": 0.2, "example": 0.4, "importance_and_relevance": 0, "materials_and_methods": 0.5, "praise": 0, "presentation_and_reporting": 0.3, "results_and_discussion": 0, "suggestion_and_solution": 0.3 }	1.7	[ { "content": "Please review this paper.", "role": "user" }, { "content": "Title: Serum lactate dehydrogenase level in preeclampsia and its correlation with disease\nseverity, maternal and perinatal outcomes\nVersion: 2 Date: 01 Jul 2024\nReviewer's report:\n1. lines 36 to 39 are out of place. We should first mention that there are predictors of adverse\nmaternal and perinatal outcome in preeclampsia cases and so on ...................\n2. Lines 46 to 47 - erroneously written\n3. Lines 81 to 82 - There is no criteria for mild preeclampsia if BP is equal to or more than\n160/110. We need to repeat BP after 15 minutes and then label\n4. Figure 1 : shows maternal complications in which study group ?\n5. There is difference in mean levels of LDH given in study group in Table 3 and 4\n6. Please if you can specify when the sample for LDH was taken - at time of induction in\nstudy or at time of IOL, early labour or elective CS. A patient presenting at 28 weeks with mild\npreeclampsia, may develop preeclampsia in coming weeks and be having high LDH which we\nmay not have evaluated", "role": "assistant" } ]	2,025
Review for 10.1186/s12905-025-03622-5	Reviewed - bmc_womens_health	Title: Serum lactate dehydrogenase level in preeclampsia and its correlation with disease severity, maternal and perinatal outcomes Version: 3 Date: 26 Jul 2024 Reviewer's report: I am satisfied with the changes made	Title: Serum lactate dehydrogenase level in preeclampsia and its correlation with disease severity, maternal and perinatal outcomes Version: 3 Date: 26 Jul 2024 Reviewer's report: I am satisfied with the changes made	BMC	12905_2025_3622_ReviewerReport_V3_R5.pdf	{ "criticism": 0, "example": 0, "importance_and_relevance": 0, "materials_and_methods": 0, "praise": 1, "presentation_and_reporting": 0, "results_and_discussion": 0, "suggestion_and_solution": 0, "total": 1 }	{ "criticism": 0, "example": 0, "importance_and_relevance": 0, "materials_and_methods": 0, "praise": 1, "presentation_and_reporting": 0, "results_and_discussion": 0, "suggestion_and_solution": 0 }	1	[ { "content": "Please review this paper.", "role": "user" }, { "content": "Title: Serum lactate dehydrogenase level in preeclampsia and its correlation with disease\nseverity, maternal and perinatal outcomes\nVersion: 3 Date: 26 Jul 2024\nReviewer's report:\nI am satisfied with the changes made", "role": "assistant" } ]	2,025
Review for 10.1186/s12905-025-03622-5	Reviewed - bmc_womens_health	Title: Serum lactate dehydrogenase level in preeclampsia and its correlation with disease severity, maternal and perinatal outcomes Version: 3 Date: 29 Jul 2024 Reviewer's report: The authors have performed an original study on the utility of uric acid to platelet ratio on the prediction for severity of preeclampsia. I have some recommendations for the authors: 1) The pathophysiology of preeclapmsia and its association with inflammation should be discussed in more detail. 2) The duration of blood sampling should be clarified, at admission to hospital or earlier? 3) There are recent studies in the literature evaluating the utility of complete blood cell indices for predicting preeclampsia. Please expand the discussion accordingly. 4) Please add more information regarding the recent biomarkers in the prediction of preeclampsia like s-flt, endoglin, etc. 5) Please underline the limitations of biomarkers in the prediction of preeclampsia. 6) the following literature may be useful: ''Tanacan, A., Sakcak, B., Ipek, G., Agaoglu, Z., Peker, A., Haksever, M., ... & Sahin, D. (2023). The role of first trimester eosinophil count and eosinophil-based complete blood cell indices in the predictiction of preeclampsia: A case-control study. Placenta, 143, 16-21.'' ''#pek, G., Tanaçan, A., A#ao#lu, Z., Ba#temur, A. G., Y#ld#z, E. G., & #ahin, D. (2024). The role of aspartate aminotransferase to platelet ratio index (APRI) in the first trimester for the prediction of superimposed preeclampsia: A case-control study from a tertiary center. Pregnancy Hypertension, 37, 101132.''	Title: Serum lactate dehydrogenase level in preeclampsia and its correlation with disease severity, maternal and perinatal outcomes Version: 3 Date: 29 Jul 2024 Reviewer's report: The authors have performed an original study on the utility of uric acid to platelet ratio on the prediction for severity of preeclampsia. I have some recommendations for the authors: 1) The pathophysiology of preeclapmsia and its association with inflammation should be discussed in more detail. 2) The duration of blood sampling should be clarified, at admission to hospital or earlier? 3) There are recent studies in the literature evaluating the utility of complete blood cell indices for predicting preeclampsia. Please expand the discussion accordingly. 4) Please add more information regarding the recent biomarkers in the prediction of preeclampsia like s-flt, endoglin, etc. 5) Please underline the limitations of biomarkers in the prediction of preeclampsia. 6) the following literature may be useful: ''Tanacan, A., Sakcak, B., Ipek, G., Agaoglu, Z., Peker, A., Haksever, M., ... & Sahin, D. (2023). The role of first trimester eosinophil count and eosinophil-based complete blood cell indices in the predictiction of preeclampsia: A case-control study. Placenta, 143, 16-21.'' ''#pek, G., Tanaçan, A., A#ao#lu, Z., Ba#temur, A. G., Y#ld#z, E. G., & #ahin, D. (2024). The role of aspartate aminotransferase to platelet ratio index (APRI) in the first trimester for the prediction of superimposed preeclampsia: A case-control study from a tertiary center. Pregnancy Hypertension, 37, 101132.''	BMC	12905_2025_3622_ReviewerReport_V3_R8.pdf	{ "criticism": 0, "example": 0, "importance_and_relevance": 1, "materials_and_methods": 7, "praise": 0, "presentation_and_reporting": 5, "results_and_discussion": 1, "suggestion_and_solution": 6, "total": 13 }	{ "criticism": 0, "example": 0, "importance_and_relevance": 0.07692307692307693, "materials_and_methods": 0.5384615384615384, "praise": 0, "presentation_and_reporting": 0.38461538461538464, "results_and_discussion": 0.07692307692307693, "suggestion_and_solution": 0.46153846153846156 }	1.538462	[ { "content": "Please review this paper.", "role": "user" }, { "content": "Title: Serum lactate dehydrogenase level in preeclampsia and its correlation with disease\nseverity, maternal and perinatal outcomes\nVersion: 3 Date: 29 Jul 2024\nReviewer's report:\nThe authors have performed an original study on the utility of uric acid to platelet ratio on the\nprediction for severity of preeclampsia. I have some recommendations for the authors:\n1) The pathophysiology of preeclapmsia and its association with inflammation should be\ndiscussed in more detail.\n2) The duration of blood sampling should be clarified, at admission to hospital or earlier?\n3) There are recent studies in the literature evaluating the utility of complete blood cell indices\nfor predicting preeclampsia. Please expand the discussion accordingly.\n4) Please add more information regarding the recent biomarkers in the prediction of preeclampsia\nlike s-flt, endoglin, etc.\n5) Please underline the limitations of biomarkers in the prediction of preeclampsia.\n6) the following literature may be useful:\n''Tanacan, A., Sakcak, B., Ipek, G., Agaoglu, Z., Peker, A., Haksever, M., ... & Sahin, D. (2023).\nThe role of first trimester eosinophil count and eosinophil-based complete blood cell indices in\nthe predictiction of preeclampsia: A case-control study. Placenta, 143, 16-21.''\n''#pek, G., Tanaçan, A., A#ao#lu, Z., Ba#temur, A. G., Y#ld#z, E. G., & #ahin, D. (2024). The\nrole of aspartate aminotransferase to platelet ratio index (APRI) in the first trimester for the\nprediction of superimposed preeclampsia: A case-control study from a tertiary center. Pregnancy\nHypertension, 37, 101132.''", "role": "assistant" } ]	2,025
Review for 10.1186/s12905-025-03622-5	Reviewed - bmc_womens_health	Title: Serum lactate dehydrogenase level in preeclampsia and its correlation with disease severity, maternal and perinatal outcomes Version: 3 Date: 31 Jul 2024 Reviewer's report: Review Serum lactate dehydrogenase level in Preeclampsia and its correlation with disease severity, maternal and perinatal outcomes Line 13 It says tocorrelate, it should say to correlate Lines 36, and 37 It says: Uric acid and the platelet-lymphocyte ratio (PLR), which can be easily calculated clinically, may predict adverse neonatal outcomes. The authors should remove this text because it is not convenient. Lines 79, 80, and 81 It says: The preeclampsia was diagnosed as mild when BP was #160/110 (which repeated after 15 minutes and then labelled) after 20 weeks of gestation in a pregnant woman with previously normal blood pressure, as well as urine dipstick reading of + 2 protein 9,15. This definition is incorrect Line 111 Statistical analysis section In this section I expected to find the Pearson correlation test or the Spearman correlation test because the authors attempted to correlate serum LDH levels with other preeclampsia severity variables, maternal outcome, and fetal outcome. The authors did not use correlation tests. The authors found significant differences, but no correlations. Introduction section The authors should add the necessary text and references to explain the role of the LDH enzyme in the pathophysiology of preeclampsia, the cause of its elevation, and its translation into the clinical field. Material and methods section There are four isoenzymes of LDH, the authors should note which of them was titrated in the laboratory or, if applicable, write that only LDH was reported without isoenzymes. The authors should take into account that the major criteria for the severity of preeclampsia are systolic and diastolic blood pressure and data on maternal organic lesions, but not fetal data. The additional fetal data that were studied in the research are of clinical interest only, because international organizations and expert groups do not consider them to be complications of preeclampsia. Results section Figure 1. Authors should note the meaning of CVA. Tables 3, 4, and 5. The authors should add the meaning of LDH. Comment The topic of research is not new, but it continues to interest the international community. The content is valuable because it shows data from a contact center, but it is local results with a descriptive design that has limitations. The authors must correct the details that have been previously noted.	Title: Serum lactate dehydrogenase level in preeclampsia and its correlation with disease severity, maternal and perinatal outcomes Version: 3 Date: 31 Jul 2024 Reviewer's report: Review Serum lactate dehydrogenase level in Preeclampsia and its correlation with disease severity, maternal and perinatal outcomes Line 13 It says tocorrelate, it should say to correlate Lines 36, and 37 It says: Uric acid and the platelet-lymphocyte ratio (PLR), which can be easily calculated clinically, may predict adverse neonatal outcomes. The authors should remove this text because it is not convenient. Lines 79, 80, and 81 It says: The preeclampsia was diagnosed as mild when BP was #160/110 (which repeated after 15 minutes and then labelled) after 20 weeks of gestation in a pregnant woman with previously normal blood pressure, as well as urine dipstick reading of + 2 protein 9,15. This definition is incorrect Line 111 Statistical analysis section In this section I expected to find the Pearson correlation test or the Spearman correlation test because the authors attempted to correlate serum LDH levels with other preeclampsia severity variables, maternal outcome, and fetal outcome. The authors did not use correlation tests. The authors found significant differences, but no correlations. Introduction section The authors should add the necessary text and references to explain the role of the LDH enzyme in the pathophysiology of preeclampsia, the cause of its elevation, and its translation into the clinical field. Material and methods section There are four isoenzymes of LDH, the authors should note which of them was titrated in the laboratory or, if applicable, write that only LDH was reported without isoenzymes. The authors should take into account that the major criteria for the severity of preeclampsia are systolic and diastolic blood pressure and data on maternal organic lesions, but not fetal data. The additional fetal data that were studied in the research are of clinical interest only, because international organizations and expert groups do not consider them to be complications of preeclampsia. Results section Figure 1. Authors should note the meaning of CVA. Tables 3, 4, and 5. The authors should add the meaning of LDH. Comment The topic of research is not new, but it continues to interest the international community. The content is valuable because it shows data from a contact center, but it is local results with a descriptive design that has limitations. The authors must correct the details that have been previously noted.	BMC	12905_2025_3622_ReviewerReport_V3_R10.pdf	{ "criticism": 3, "example": 4, "importance_and_relevance": 2, "materials_and_methods": 8, "praise": 2, "presentation_and_reporting": 8, "results_and_discussion": 4, "suggestion_and_solution": 8, "total": 17 }	{ "criticism": 0.17647058823529413, "example": 0.23529411764705882, "importance_and_relevance": 0.11764705882352941, "materials_and_methods": 0.47058823529411764, "praise": 0.11764705882352941, "presentation_and_reporting": 0.47058823529411764, "results_and_discussion": 0.23529411764705882, "suggestion_and_solution": 0.47058823529411764 }	2.294118	[ { "content": "Please review this paper.", "role": "user" }, { "content": "Title: Serum lactate dehydrogenase level in preeclampsia and its correlation with disease\nseverity, maternal and perinatal outcomes\nVersion: 3 Date: 31 Jul 2024\nReviewer's report:\nReview\nSerum lactate dehydrogenase level in Preeclampsia and its correlation with disease severity,\nmaternal and perinatal outcomes\nLine 13\nIt says tocorrelate, it should say to correlate\nLines 36, and 37\nIt says: Uric acid and the platelet-lymphocyte ratio (PLR), which can be easily calculated\nclinically, may predict adverse neonatal outcomes.\nThe authors should remove this text because it is not convenient.\nLines 79, 80, and 81\nIt says: The preeclampsia was diagnosed as mild when BP was #160/110 (which repeated after\n15 minutes and then labelled) after 20 weeks of gestation in a pregnant woman with previously\nnormal blood pressure, as well as urine dipstick reading of + 2 protein 9,15.\nThis definition is incorrect\nLine 111\nStatistical analysis section\nIn this section I expected to find the Pearson correlation test or the Spearman correlation test\nbecause the authors attempted to correlate serum LDH levels with other preeclampsia severity\nvariables, maternal outcome, and fetal outcome. The authors did not use correlation tests. The\nauthors found significant differences, but no correlations.\nIntroduction section\nThe authors should add the necessary text and references to explain the role of the LDH enzyme\nin the pathophysiology of preeclampsia, the cause of its elevation, and its translation into the\nclinical field.\nMaterial and methods section\nThere are four isoenzymes of LDH, the authors should note which of them was titrated in the\nlaboratory or, if applicable, write that only LDH was reported without isoenzymes.\nThe authors should take into account that the major criteria for the severity of preeclampsia\nare systolic and diastolic blood pressure and data on maternal organic lesions, but not fetal\ndata. The additional fetal data that were studied in the research are of clinical interest only,\nbecause international organizations and expert groups do not consider them to be complications\nof preeclampsia.\nResults section\nFigure 1. Authors should note the meaning of CVA.\nTables 3, 4, and 5. The authors should add the meaning of LDH.\nComment\nThe topic of research is not new, but it continues to interest the international community. The\ncontent is valuable because it shows data from a contact center, but it is local results with\na descriptive design that has limitations. The authors must correct the details that have been\npreviously noted.", "role": "assistant" } ]	2,025
Review for 10.1186/s12905-025-03622-5	Reviewed - bmc_womens_health	Title: Serum lactate dehydrogenase level in preeclampsia and its correlation with disease severity, maternal and perinatal outcomes Version: 4 Date: 20 Aug 2024 Reviewer's report: The authors have performed the recommended revisions, the manuscript may be accepted in its present form.	Title: Serum lactate dehydrogenase level in preeclampsia and its correlation with disease severity, maternal and perinatal outcomes Version: 4 Date: 20 Aug 2024 Reviewer's report: The authors have performed the recommended revisions, the manuscript may be accepted in its present form.	BMC	12905_2025_3622_ReviewerReport_V4_R8.pdf	{ "criticism": 0, "example": 0, "importance_and_relevance": 0, "materials_and_methods": 0, "praise": 1, "presentation_and_reporting": 0, "results_and_discussion": 0, "suggestion_and_solution": 1, "total": 1 }	{ "criticism": 0, "example": 0, "importance_and_relevance": 0, "materials_and_methods": 0, "praise": 1, "presentation_and_reporting": 0, "results_and_discussion": 0, "suggestion_and_solution": 1 }	2	[ { "content": "Please review this paper.", "role": "user" }, { "content": "Title: Serum lactate dehydrogenase level in preeclampsia and its correlation with disease\nseverity, maternal and perinatal outcomes\nVersion: 4 Date: 20 Aug 2024\nReviewer's report:\nThe authors have performed the recommended revisions, the manuscript may be accepted in its\npresent form.", "role": "assistant" } ]	2,025
Review for 10.1186/s12905-025-03622-5	Reviewed - bmc_womens_health	Title: Serum lactate dehydrogenase level in preeclampsia and its correlation with disease severity, maternal and perinatal outcomes Version: 4 Date: 21 Aug 2024 Reviewer's report: Serum lactate dehydrogenase level in Preeclampsia and its correlation with disease severity, maternal and perinatal outcomes Authors carried out all recommendations from the first round of review. The manuscript can be published without changes.	Title: Serum lactate dehydrogenase level in preeclampsia and its correlation with disease severity, maternal and perinatal outcomes Version: 4 Date: 21 Aug 2024 Reviewer's report: Serum lactate dehydrogenase level in Preeclampsia and its correlation with disease severity, maternal and perinatal outcomes Authors carried out all recommendations from the first round of review. The manuscript can be published without changes.	BMC	12905_2025_3622_ReviewerReport_V4_R10.pdf	{ "criticism": 0, "example": 0, "importance_and_relevance": 0, "materials_and_methods": 0, "praise": 1, "presentation_and_reporting": 0, "results_and_discussion": 0, "suggestion_and_solution": 1, "total": 2 }	{ "criticism": 0, "example": 0, "importance_and_relevance": 0, "materials_and_methods": 0, "praise": 0.5, "presentation_and_reporting": 0, "results_and_discussion": 0, "suggestion_and_solution": 0.5 }	1	[ { "content": "Please review this paper.", "role": "user" }, { "content": "Title: Serum lactate dehydrogenase level in preeclampsia and its correlation with disease\nseverity, maternal and perinatal outcomes\nVersion: 4 Date: 21 Aug 2024\nReviewer's report:\nSerum lactate dehydrogenase level in Preeclampsia and its correlation with disease severity,\nmaternal and perinatal outcomes\nAuthors carried out all recommendations from the first round of review.\nThe manuscript can be published without changes.", "role": "assistant" } ]	2,025
Review for 10.1186/s12905-025-03636-z	Reviewed - bmc_womens_health	Title: Decomposing the effect of women's educational status on fertility across the six geo- political zones in Nigeria: 2003-2018 Version: 1 Date: 27 Sep 2024 Reviewer's report: I have reviewed the manuscript and its aim was to decompose the effect of women’s literacy status on fertility in the geo-political zone of Nigeria. The study uses Demographic and Health Survey data for the period 2003 to 2018. The paper has attempted to perform decomposition analysis; however, the execution of the method is not easy to follow and replicate. The terms ‘educated’ and ‘uneducated’ versus ‘literate’ and ‘illiterate’ are used interchangeably when in the strictest sense they can mean different things. The methods section of the manuscript needs to be streamlined and remove excess details such as explanations of household listing. It also needs to be clear of the DHS datasets were pooled or analyzed separately. Also, how the weights were applied. In this section, there is a mix of font type. In the statistical analysis section, it is not clear why we have a number of estimates of fertility: children ever borne, total fertility rates, parity progression ratios. What is the purpose of each of these measures? How are they used in decomposition analysis? What is the purpose of using risk difference? Why was the heat map used? Provide an explanation besides pointing to the literature. The results of the logistic regression analysis for the Blinder-Oaxaca decomposition are not provided. The magnitude of the contributing factors is not provided. The manuscript requires proofreading and editing.	Title: Decomposing the effect of women's educational status on fertility across the six geo- political zones in Nigeria: 2003-2018 Version: 1 Date: 27 Sep 2024 Reviewer's report: I have reviewed the manuscript and its aim was to decompose the effect of women’s literacy status on fertility in the geo-political zone of Nigeria. The study uses Demographic and Health Survey data for the period 2003 to 2018. The paper has attempted to perform decomposition analysis; however, the execution of the method is not easy to follow and replicate. The terms ‘educated’ and ‘uneducated’ versus ‘literate’ and ‘illiterate’ are used interchangeably when in the strictest sense they can mean different things. The methods section of the manuscript needs to be streamlined and remove excess details such as explanations of household listing. It also needs to be clear of the DHS datasets were pooled or analyzed separately. Also, how the weights were applied. In this section, there is a mix of font type. In the statistical analysis section, it is not clear why we have a number of estimates of fertility: children ever borne, total fertility rates, parity progression ratios. What is the purpose of each of these measures? How are they used in decomposition analysis? What is the purpose of using risk difference? Why was the heat map used? Provide an explanation besides pointing to the literature. The results of the logistic regression analysis for the Blinder-Oaxaca decomposition are not provided. The magnitude of the contributing factors is not provided. The manuscript requires proofreading and editing.	BMC	12905_2025_3636_ReviewerReport_V1_R2.pdf	{ "criticism": 3, "example": 0, "importance_and_relevance": 0, "materials_and_methods": 10, "praise": 0, "presentation_and_reporting": 4, "results_and_discussion": 1, "suggestion_and_solution": 4, "total": 17 }	{ "criticism": 0.17647058823529413, "example": 0, "importance_and_relevance": 0, "materials_and_methods": 0.5882352941176471, "praise": 0, "presentation_and_reporting": 0.23529411764705882, "results_and_discussion": 0.058823529411764705, "suggestion_and_solution": 0.23529411764705882 }	1.294118	[ { "content": "Please review this paper.", "role": "user" }, { "content": "Title: Decomposing the effect of women's educational status on fertility across the six geo-\npolitical zones in Nigeria: 2003-2018\nVersion: 1 Date: 27 Sep 2024\nReviewer's report:\nI have reviewed the manuscript and its aim was to decompose the effect of women’s literacy\nstatus on fertility in the geo-political zone of Nigeria. The study uses Demographic and Health\nSurvey data for the period 2003 to 2018. The paper has attempted to perform decomposition\nanalysis; however, the execution of the method is not easy to follow and replicate. The terms\n‘educated’ and ‘uneducated’ versus ‘literate’ and ‘illiterate’ are used interchangeably when in\nthe strictest sense they can mean different things. The methods section of the manuscript needs\nto be streamlined and remove excess details such as explanations of household listing. It also\nneeds to be clear of the DHS datasets were pooled or analyzed separately. Also, how the weights\nwere applied. In this section, there is a mix of font type.\nIn the statistical analysis section, it is not clear why we have a number of estimates of fertility:\nchildren ever borne, total fertility rates, parity progression ratios. What is the purpose of each\nof these measures? How are they used in decomposition analysis? What is the purpose of using\nrisk difference? Why was the heat map used? Provide an explanation besides pointing to the\nliterature.\nThe results of the logistic regression analysis for the Blinder-Oaxaca decomposition are not\nprovided.\nThe magnitude of the contributing factors is not provided.\nThe manuscript requires proofreading and editing.", "role": "assistant" } ]	2,025
Review for 10.1186/s12905-025-03636-z	Reviewed - bmc_womens_health	Title: Decomposing the effect of women's educational status on fertility across the six geo- political zones in Nigeria: 2003-2018 Version: 1 Date: 29 Sep 2024 Reviewer: Elhakim Ibrahim Reviewer's report: The study addresses a subject of wide public health interest and employs an appropriate empirical approach to achieving its core objective. The paper reflects originality and substantial contribution to knowledge on the topic. The empirical strategies are well documented. However, I would like to suggest, except for evidence of multicollinearity, including some variables such as “ever used of family planning”, “relationship to household head”, “perceived problem getting permission to seek healthcare (not a big problem v a big problem)”, and “perceived problem getting money to seek healthcare (not a big problem v a big problem)”. These variables have been documented to play a crucial role in past studies. I believe that addressing this minor observation could enhance the validity of the study findings.	Title: Decomposing the effect of women's educational status on fertility across the six geo- political zones in Nigeria: 2003-2018 Version: 1 Date: 29 Sep 2024 Reviewer: Elhakim Ibrahim Reviewer's report: The study addresses a subject of wide public health interest and employs an appropriate empirical approach to achieving its core objective. The paper reflects originality and substantial contribution to knowledge on the topic. The empirical strategies are well documented. However, I would like to suggest, except for evidence of multicollinearity, including some variables such as “ever used of family planning”, “relationship to household head”, “perceived problem getting permission to seek healthcare (not a big problem v a big problem)”, and “perceived problem getting money to seek healthcare (not a big problem v a big problem)”. These variables have been documented to play a crucial role in past studies. I believe that addressing this minor observation could enhance the validity of the study findings.	BMC	12905_2025_3636_ReviewerReport_V1_R3.pdf	{ "criticism": 0, "example": 0, "importance_and_relevance": 3, "materials_and_methods": 3, "praise": 4, "presentation_and_reporting": 0, "results_and_discussion": 1, "suggestion_and_solution": 2, "total": 6 }	{ "criticism": 0, "example": 0, "importance_and_relevance": 0.5, "materials_and_methods": 0.5, "praise": 0.6666666666666666, "presentation_and_reporting": 0, "results_and_discussion": 0.16666666666666666, "suggestion_and_solution": 0.3333333333333333 }	2.166667	[ { "content": "Please review this paper.", "role": "user" }, { "content": "Title: Decomposing the effect of women's educational status on fertility across the six geo-\npolitical zones in Nigeria: 2003-2018\nVersion: 1 Date: 29 Sep 2024\nReviewer: Elhakim Ibrahim\nReviewer's report:\nThe study addresses a subject of wide public health interest and employs an appropriate\nempirical approach to achieving its core objective. The paper reflects originality and substantial\ncontribution to knowledge on the topic. The empirical strategies are well documented.\nHowever, I would like to suggest, except for evidence of multicollinearity, including some\nvariables such as “ever used of family planning”, “relationship to household head”, “perceived\nproblem getting permission to seek healthcare (not a big problem v a big problem)”, and\n“perceived problem getting money to seek healthcare (not a big problem v a big problem)”.\nThese variables have been documented to play a crucial role in past studies. I believe that\naddressing this minor observation could enhance the validity of the study findings.", "role": "assistant" } ]	2,025
Review for 10.1186/s12905-025-03636-z	Reviewed - bmc_womens_health	Title: Decomposing the effect of women's educational status on fertility across the six geo- political zones in Nigeria: 2003-2018 Version: 1 Date: 14 Oct 2024 Reviewer's report: This study is interesting. However, for the manuscript to be in an acceptable form for publication, I advise the authors consider my comments below to revise the manuscript. Abstract - The study uses a repeated cross-sectional analysis design so this should be stated - The Background should include additional aims of the study since the study does more than quantify the fertility rate between uneducated and educated women. - Why is the total stated as “nTotal”? The way in which the DHS survey years are stated and the total sample size should be separate sentences. - Why stated proportions with no education for 2003 and 2014? The choice of those two years in the abstract seems random. Introduction - The literature on the role of mass education on fertility in sub-Saharan Africa as well as the role of abortion can be discussed since it contributed to fertility decline in sub-Saharan Africa. - The authors need to comment on the extant fertility and education studies in Nigeria. These seem to be missing. - It is not clear why the authors choose to assess fertility across four surveys. The rationale for all the survey years should be more evident. - Examples of studies with references are needed to explain the sentence about how fertility varies due to diversities and differences based on sociocultural factors. Methods - Variable description – for the age at first marriage variable, how were never married women classified? This needs to be indicated. If it is an oversight, it has to be rectified. - Region was also not reported as a variable in the Variable description section - The variable “neighbourhood socioeconomic status” is mentioned under the “statistical analysis” section but is not mentioned in the “variable description” - How the decomposition values in the heatmap are arranged by survey year and region needs to be explained. Results - Tables 1 and 2 need to be looked at. Perhaps decimal places can be reduced to one place so that all the columns fit well on each table. - Why is the parity progression ratio needed? The concept is technical and needs explanation. However, its inclusion should be justified. - For Figure 1 – perhaps range plots would be best. It is not clear why some of the points are an X and others an X with a line. - Figure 3 needs to be changed. The y-axis needs better labelling. Does it indicate uneducated and educated women across study waves? Why is the figure dark? - Figure 5 has several points that may not be needed. The values across the waves and regions by the different factors are too many. Does all this data add value to the study. The authors could consider the decomposition analysis using two waves - 2003 and 2018. This would indicate more recent implications. Discussion - More discussion in relation to the regions should be mentioned. What have other findings stated on the regional-education fertility differences.	Title: Decomposing the effect of women's educational status on fertility across the six geo- political zones in Nigeria: 2003-2018 Version: 1 Date: 14 Oct 2024 Reviewer's report: This study is interesting. However, for the manuscript to be in an acceptable form for publication, I advise the authors consider my comments below to revise the manuscript. Abstract - The study uses a repeated cross-sectional analysis design so this should be stated - The Background should include additional aims of the study since the study does more than quantify the fertility rate between uneducated and educated women. - Why is the total stated as “nTotal”? The way in which the DHS survey years are stated and the total sample size should be separate sentences. - Why stated proportions with no education for 2003 and 2014? The choice of those two years in the abstract seems random. Introduction - The literature on the role of mass education on fertility in sub-Saharan Africa as well as the role of abortion can be discussed since it contributed to fertility decline in sub-Saharan Africa. - The authors need to comment on the extant fertility and education studies in Nigeria. These seem to be missing. - It is not clear why the authors choose to assess fertility across four surveys. The rationale for all the survey years should be more evident. - Examples of studies with references are needed to explain the sentence about how fertility varies due to diversities and differences based on sociocultural factors. Methods - Variable description – for the age at first marriage variable, how were never married women classified? This needs to be indicated. If it is an oversight, it has to be rectified. - Region was also not reported as a variable in the Variable description section - The variable “neighbourhood socioeconomic status” is mentioned under the “statistical analysis” section but is not mentioned in the “variable description” - How the decomposition values in the heatmap are arranged by survey year and region needs to be explained. Results - Tables 1 and 2 need to be looked at. Perhaps decimal places can be reduced to one place so that all the columns fit well on each table. - Why is the parity progression ratio needed? The concept is technical and needs explanation. However, its inclusion should be justified. - For Figure 1 – perhaps range plots would be best. It is not clear why some of the points are an X and others an X with a line. - Figure 3 needs to be changed. The y-axis needs better labelling. Does it indicate uneducated and educated women across study waves? Why is the figure dark? - Figure 5 has several points that may not be needed. The values across the waves and regions by the different factors are too many. Does all this data add value to the study. The authors could consider the decomposition analysis using two waves - 2003 and 2018. This would indicate more recent implications. Discussion - More discussion in relation to the regions should be mentioned. What have other findings stated on the regional-education fertility differences.	BMC	12905_2025_3636_ReviewerReport_V1_R5.pdf	{ "criticism": 4, "example": 3, "importance_and_relevance": 2, "materials_and_methods": 12, "praise": 2, "presentation_and_reporting": 17, "results_and_discussion": 5, "suggestion_and_solution": 22, "total": 35 }	{ "criticism": 0.11428571428571428, "example": 0.08571428571428572, "importance_and_relevance": 0.05714285714285714, "materials_and_methods": 0.34285714285714286, "praise": 0.05714285714285714, "presentation_and_reporting": 0.4857142857142857, "results_and_discussion": 0.14285714285714285, "suggestion_and_solution": 0.6285714285714286 }	1.914286	[ { "content": "Please review this paper.", "role": "user" }, { "content": "Title: Decomposing the effect of women's educational status on fertility across the six geo-\npolitical zones in Nigeria: 2003-2018\nVersion: 1 Date: 14 Oct 2024\nReviewer's report:\nThis study is interesting. However, for the manuscript to be in an acceptable form for publication,\nI advise the authors consider my comments below to revise the manuscript.\nAbstract\n- The study uses a repeated cross-sectional analysis design so this should be stated\n- The Background should include additional aims of the study since the study does more than\nquantify the fertility rate between uneducated and educated women.\n- Why is the total stated as “nTotal”? The way in which the DHS survey years are stated and\nthe total sample size should be separate sentences.\n- Why stated proportions with no education for 2003 and 2014? The choice of those two years\nin the abstract seems random.\nIntroduction\n- The literature on the role of mass education on fertility in sub-Saharan Africa as well as the\nrole of abortion can be discussed since it contributed to fertility decline in sub-Saharan Africa.\n- The authors need to comment on the extant fertility and education studies in Nigeria. These\nseem to be missing.\n- It is not clear why the authors choose to assess fertility across four surveys. The rationale for\nall the survey years should be more evident.\n- Examples of studies with references are needed to explain the sentence about how fertility\nvaries due to diversities and differences based on sociocultural factors.\nMethods\n- Variable description – for the age at first marriage variable, how were never married women\nclassified? This needs to be indicated. If it is an oversight, it has to be rectified.\n- Region was also not reported as a variable in the Variable description section\n- The variable “neighbourhood socioeconomic status” is mentioned under the “statistical\nanalysis” section but is not mentioned in the “variable description”\n- How the decomposition values in the heatmap are arranged by survey year and region needs\nto be explained.\nResults\n- Tables 1 and 2 need to be looked at. Perhaps decimal places can be reduced to one place so\nthat all the columns fit well on each table.\n- Why is the parity progression ratio needed? The concept is technical and needs explanation.\nHowever, its inclusion should be justified.\n- For Figure 1 – perhaps range plots would be best. It is not clear why some of the points are\nan X and others an X with a line.\n- Figure 3 needs to be changed. The y-axis needs better labelling. Does it indicate uneducated\nand educated women across study waves? Why is the figure dark?\n- Figure 5 has several points that may not be needed. The values across the waves and regions\nby the different factors are too many. Does all this data add value to the study. The authors could\nconsider the decomposition analysis using two waves - 2003 and 2018. This would indicate\nmore recent implications.\nDiscussion\n- More discussion in relation to the regions should be mentioned. What have other findings\nstated on the regional-education fertility differences.", "role": "assistant" } ]	2,025
Review for 10.1186/s12905-025-03636-z	Reviewed - bmc_womens_health	Title: Decomposing the effect of women's educational status on fertility across the six geo- political zones in Nigeria: 2003-2018 Version: 2 Date: 10 Nov 2024 Reviewer's report: I have reviewed the manuscript for the second time. I still have the following comments: Methods section: How was the weighting done? The explanation of weighting is general rather than specific. Application of the direct method of estimating total fertility rate (TFR) using Demographic and Health Survey (DHS) data is not clearly described. Merely referencing Moultrie et al 2013 is not adequate. There is a lot involved in applying the direct method of estimating TFR when using DHS data. Add some more specific elaboration on how this was done. A new variable has been introduced “neighbourhood socioeconomic status” How was this variable constructed? It is also not in Table 1 and Table 2. Results section: Use of the terms ‘educated’ and ‘uneducated’ versus ‘literate’ and ‘illiterate’ in the results is inconsistent. Table 2 and Figure 4 use ‘educated’ and ‘uneducated’ while Figures 1,2 and 3 use ‘literate’ and ‘illiterate’ Figure 2 with parity progression ratios (PPRs) is still part of the manuscript results despite the responses to the comments indicating that this part has been removed. In fact, the PPRs results in Figure 2 have not been interpreted as expected. In Figure 4, the Risk Differences (RDs) have 2-decimal places while numbers being subtracted have 1-decimal place. Ensure there is consistency. The weights in Figure 4 have not been interpreted. Results from the Random Effects Model are presented in Figure 4 and yet there is no mention of this in the methods. The decomposition results in Figure 5 have not been fully interpreted as expected. The current interpretation is general rather than analytical for the Blinder-Oaxaca regression.	Title: Decomposing the effect of women's educational status on fertility across the six geo- political zones in Nigeria: 2003-2018 Version: 2 Date: 10 Nov 2024 Reviewer's report: I have reviewed the manuscript for the second time. I still have the following comments: Methods section: How was the weighting done? The explanation of weighting is general rather than specific. Application of the direct method of estimating total fertility rate (TFR) using Demographic and Health Survey (DHS) data is not clearly described. Merely referencing Moultrie et al 2013 is not adequate. There is a lot involved in applying the direct method of estimating TFR when using DHS data. Add some more specific elaboration on how this was done. A new variable has been introduced “neighbourhood socioeconomic status” How was this variable constructed? It is also not in Table 1 and Table 2. Results section: Use of the terms ‘educated’ and ‘uneducated’ versus ‘literate’ and ‘illiterate’ in the results is inconsistent. Table 2 and Figure 4 use ‘educated’ and ‘uneducated’ while Figures 1,2 and 3 use ‘literate’ and ‘illiterate’ Figure 2 with parity progression ratios (PPRs) is still part of the manuscript results despite the responses to the comments indicating that this part has been removed. In fact, the PPRs results in Figure 2 have not been interpreted as expected. In Figure 4, the Risk Differences (RDs) have 2-decimal places while numbers being subtracted have 1-decimal place. Ensure there is consistency. The weights in Figure 4 have not been interpreted. Results from the Random Effects Model are presented in Figure 4 and yet there is no mention of this in the methods. The decomposition results in Figure 5 have not been fully interpreted as expected. The current interpretation is general rather than analytical for the Blinder-Oaxaca regression.	BMC	12905_2025_3636_ReviewerReport_V2_R2.pdf	{ "criticism": 8, "example": 5, "importance_and_relevance": 0, "materials_and_methods": 8, "praise": 0, "presentation_and_reporting": 10, "results_and_discussion": 5, "suggestion_and_solution": 2, "total": 18 }	{ "criticism": 0.4444444444444444, "example": 0.2777777777777778, "importance_and_relevance": 0, "materials_and_methods": 0.4444444444444444, "praise": 0, "presentation_and_reporting": 0.5555555555555556, "results_and_discussion": 0.2777777777777778, "suggestion_and_solution": 0.1111111111111111 }	2.111111	[ { "content": "Please review this paper.", "role": "user" }, { "content": "Title: Decomposing the effect of women's educational status on fertility across the six geo-\npolitical zones in Nigeria: 2003-2018\nVersion: 2 Date: 10 Nov 2024\nReviewer's report:\nI have reviewed the manuscript for the second time. I still have the following comments:\nMethods section:\nHow was the weighting done? The explanation of weighting is general rather than specific.\nApplication of the direct method of estimating total fertility rate (TFR) using Demographic and\nHealth Survey (DHS) data is not clearly described. Merely referencing Moultrie et al 2013 is not\nadequate. There is a lot involved in applying the direct method of estimating TFR when using\nDHS data. Add some more specific elaboration on how this was done.\nA new variable has been introduced “neighbourhood socioeconomic status” How was this\nvariable constructed? It is also not in Table 1 and Table 2.\nResults section:\nUse of the terms ‘educated’ and ‘uneducated’ versus ‘literate’ and ‘illiterate’ in the results is\ninconsistent. Table 2 and Figure 4 use ‘educated’ and ‘uneducated’ while Figures 1,2 and 3 use\n‘literate’ and ‘illiterate’\nFigure 2 with parity progression ratios (PPRs) is still part of the manuscript results despite the\nresponses to the comments indicating that this part has been removed. In fact, the PPRs results\nin Figure 2 have not been interpreted as expected.\nIn Figure 4, the Risk Differences (RDs) have 2-decimal places while numbers being subtracted\nhave 1-decimal place. Ensure there is consistency. The weights in Figure 4 have not been\ninterpreted. Results from the Random Effects Model are presented in Figure 4 and yet there is\nno mention of this in the methods.\nThe decomposition results in Figure 5 have not been fully interpreted as expected. The current\ninterpretation is general rather than analytical for the Blinder-Oaxaca regression.", "role": "assistant" } ]	2,025
Review for 10.1186/s12905-025-03636-z	Reviewed - bmc_womens_health	Title: Decomposing the effect of women's educational status on fertility across the six geo- political zones in Nigeria: 2003-2018 Version: 2 Date: 14 Nov 2024 Reviewer's report: -The authors still need to report what has been studied on this subject in Nigeria. That seems to still be missing in the Introduction. - Variable Description: How was the analysis adjusted to fit the age of respondents? - The ‘Variable Description’ and ‘Statistical Analysis’ sections have a different font style which need to be changed. - A few comments from the previous review were responded to with cursory comments and thus still need to be addressed. For example, how were women with no births and those not married categorized in the study? This was still not explained when age at first birth and marriage were explained. - Also, the authors state that the way in which some variables are measured are reported in another paper. However, some readers may not have access to those additional papers, so at least the response categories for the neighborhood socioeconomic status variable should be stated. - The authors fail to explain the need for the parity progression ratio figure in the manuscript but indicate in the reviewers’ comments that they have removed this data from the study. The authors should resolve this discrepancy. - How the decomposition values in the heatmap are arranged by survey year and region still needs additional explanation. The sentence that has been included does not provide information on why the regions and survey years are arranged in that order.	Title: Decomposing the effect of women's educational status on fertility across the six geo- political zones in Nigeria: 2003-2018 Version: 2 Date: 14 Nov 2024 Reviewer's report: -The authors still need to report what has been studied on this subject in Nigeria. That seems to still be missing in the Introduction. - Variable Description: How was the analysis adjusted to fit the age of respondents? - The ‘Variable Description’ and ‘Statistical Analysis’ sections have a different font style which need to be changed. - A few comments from the previous review were responded to with cursory comments and thus still need to be addressed. For example, how were women with no births and those not married categorized in the study? This was still not explained when age at first birth and marriage were explained. - Also, the authors state that the way in which some variables are measured are reported in another paper. However, some readers may not have access to those additional papers, so at least the response categories for the neighborhood socioeconomic status variable should be stated. - The authors fail to explain the need for the parity progression ratio figure in the manuscript but indicate in the reviewers’ comments that they have removed this data from the study. The authors should resolve this discrepancy. - How the decomposition values in the heatmap are arranged by survey year and region still needs additional explanation. The sentence that has been included does not provide information on why the regions and survey years are arranged in that order.	BMC	12905_2025_3636_ReviewerReport_V2_R5.pdf	{ "criticism": 4, "example": 0, "importance_and_relevance": 0, "materials_and_methods": 8, "praise": 0, "presentation_and_reporting": 8, "results_and_discussion": 0, "suggestion_and_solution": 6, "total": 13 }	{ "criticism": 0.3076923076923077, "example": 0, "importance_and_relevance": 0, "materials_and_methods": 0.6153846153846154, "praise": 0, "presentation_and_reporting": 0.6153846153846154, "results_and_discussion": 0, "suggestion_and_solution": 0.46153846153846156 }	2	[ { "content": "Please review this paper.", "role": "user" }, { "content": "Title: Decomposing the effect of women's educational status on fertility across the six geo-\npolitical zones in Nigeria: 2003-2018\nVersion: 2 Date: 14 Nov 2024\nReviewer's report:\n-The authors still need to report what has been studied on this subject in Nigeria. That seems\nto still be missing in the Introduction.\n- Variable Description: How was the analysis adjusted to fit the age of respondents?\n- The ‘Variable Description’ and ‘Statistical Analysis’ sections have a different font style which\nneed to be changed.\n- A few comments from the previous review were responded to with cursory comments and thus\nstill need to be addressed. For example, how were women with no births and those not married\ncategorized in the study? This was still not explained when age at first birth and marriage were\nexplained.\n- Also, the authors state that the way in which some variables are measured are reported in\nanother paper. However, some readers may not have access to those additional papers, so at least\nthe response categories for the neighborhood socioeconomic status variable should be stated.\n- The authors fail to explain the need for the parity progression ratio figure in the manuscript\nbut indicate in the reviewers’ comments that they have removed this data from the study. The\nauthors should resolve this discrepancy.\n- How the decomposition values in the heatmap are arranged by survey year and region still\nneeds additional explanation. The sentence that has been included does not provide information\non why the regions and survey years are arranged in that order.", "role": "assistant" } ]	2,025
Review for 10.1186/s12905-025-03636-z	Reviewed - bmc_womens_health	Title: Decomposing the effect of women's educational status on fertility across the six geo- political zones in Nigeria: 2003-2018 Version: 4 Date: 16 Jan 2025 Reviewer's report: I have reviewed the manuscript, and I note that a number of my earlier observations have been addressed and there is some improvement in the quality of the manuscript. However, I still have some lingering comments: Methods section Study design and Data: The manuscripts states that ‘women’s files’ were used in the analysis, but it is silent on the ‘child recode’ files that were used in the computation of total fertility rate (TFR). Variable description: The manuscript states that the dependent variable is children ever born (CEB) and the mean was computed (MCEB). The TFR was also calculated. For the sake of clarity, what was used to compute the Risk Differences (RDs)? Is it the MCEB or TFR? This is not clear. If the RD values were computed using MCEB, then what was the purpose of calculating TFR? The application of the direct method of estimating TFR using Demographic and Health Survey (DHS) data as referenced in Moultrie et al 2013 has been elaborated. The steps of computing the TFR have been outlined, however, there is a part that is still not explained that sums up the age-specific fertility rates (ASFRs) into TFR. Also, how this was done by education status? Elaborate. Minor comment Proofread and edit the manuscript and ensure consistence in the use of ‘educated’ and ‘uneducated’ versus ‘literate’ and ‘illiterate’	Title: Decomposing the effect of women's educational status on fertility across the six geo- political zones in Nigeria: 2003-2018 Version: 4 Date: 16 Jan 2025 Reviewer's report: I have reviewed the manuscript, and I note that a number of my earlier observations have been addressed and there is some improvement in the quality of the manuscript. However, I still have some lingering comments: Methods section Study design and Data: The manuscripts states that ‘women’s files’ were used in the analysis, but it is silent on the ‘child recode’ files that were used in the computation of total fertility rate (TFR). Variable description: The manuscript states that the dependent variable is children ever born (CEB) and the mean was computed (MCEB). The TFR was also calculated. For the sake of clarity, what was used to compute the Risk Differences (RDs)? Is it the MCEB or TFR? This is not clear. If the RD values were computed using MCEB, then what was the purpose of calculating TFR? The application of the direct method of estimating TFR using Demographic and Health Survey (DHS) data as referenced in Moultrie et al 2013 has been elaborated. The steps of computing the TFR have been outlined, however, there is a part that is still not explained that sums up the age-specific fertility rates (ASFRs) into TFR. Also, how this was done by education status? Elaborate. Minor comment Proofread and edit the manuscript and ensure consistence in the use of ‘educated’ and ‘uneducated’ versus ‘literate’ and ‘illiterate’	BMC	12905_2025_3636_ReviewerReport_V4_R2.pdf	{ "criticism": 3, "example": 0, "importance_and_relevance": 0, "materials_and_methods": 8, "praise": 1, "presentation_and_reporting": 1, "results_and_discussion": 0, "suggestion_and_solution": 1, "total": 13 }	{ "criticism": 0.23076923076923078, "example": 0, "importance_and_relevance": 0, "materials_and_methods": 0.6153846153846154, "praise": 0.07692307692307693, "presentation_and_reporting": 0.07692307692307693, "results_and_discussion": 0, "suggestion_and_solution": 0.07692307692307693 }	1.076923	[ { "content": "Please review this paper.", "role": "user" }, { "content": "Title: Decomposing the effect of women's educational status on fertility across the six geo-\npolitical zones in Nigeria: 2003-2018\nVersion: 4 Date: 16 Jan 2025\nReviewer's report:\nI have reviewed the manuscript, and I note that a number of my earlier observations have been\naddressed and there is some improvement in the quality of the manuscript. However, I still have\nsome lingering comments:\nMethods section\nStudy design and Data: The manuscripts states that ‘women’s files’ were used in the analysis,\nbut it is silent on the ‘child recode’ files that were used in the computation of total fertility rate\n(TFR).\nVariable description: The manuscript states that the dependent variable is children ever born\n(CEB) and the mean was computed (MCEB). The TFR was also calculated. For the sake of\nclarity, what was used to compute the Risk Differences (RDs)? Is it the MCEB or TFR? This is\nnot clear. If the RD values were computed using MCEB, then what was the purpose of calculating\nTFR?\nThe application of the direct method of estimating TFR using Demographic and Health Survey\n(DHS) data as referenced in Moultrie et al 2013 has been elaborated. The steps of computing\nthe TFR have been outlined, however, there is a part that is still not explained that sums up\nthe age-specific fertility rates (ASFRs) into TFR. Also, how this was done by education status?\nElaborate.\nMinor comment\nProofread and edit the manuscript and ensure consistence in the use of ‘educated’ and\n‘uneducated’ versus ‘literate’ and ‘illiterate’", "role": "assistant" } ]	2,025
Review for 10.1186/s12905-025-03636-z	Reviewed - bmc_womens_health	Title: Decomposing the effect of women's educational status on fertility across the six geo- political zones in Nigeria: 2003-2018 Version: 4 Date: 17 Jan 2025 Reviewer's report: I have no additional comments for the authors.	Title: Decomposing the effect of women's educational status on fertility across the six geo- political zones in Nigeria: 2003-2018 Version: 4 Date: 17 Jan 2025 Reviewer's report: I have no additional comments for the authors.	BMC	12905_2025_3636_ReviewerReport_V4_R5.pdf	{ "criticism": 1, "example": 0, "importance_and_relevance": 0, "materials_and_methods": 0, "praise": 0, "presentation_and_reporting": 0, "results_and_discussion": 0, "suggestion_and_solution": 0, "total": 1 }	{ "criticism": 1, "example": 0, "importance_and_relevance": 0, "materials_and_methods": 0, "praise": 0, "presentation_and_reporting": 0, "results_and_discussion": 0, "suggestion_and_solution": 0 }	1	[ { "content": "Please review this paper.", "role": "user" }, { "content": "Title: Decomposing the effect of women's educational status on fertility across the six geo-\npolitical zones in Nigeria: 2003-2018\nVersion: 4 Date: 17 Jan 2025\nReviewer's report:\nI have no additional comments for the authors.", "role": "assistant" } ]	2,025
Review for 10.1186/s12905-025-03636-z	Reviewed - bmc_womens_health	Title: Decomposing the effect of women's educational status on fertility across the six geo- political zones in Nigeria: 2003-2018 Version: 4 Date: 12 Feb 2025 Reviewer: Elhakim Ibrahim Reviewer's report: All concerns raised in the previous submission had been addressed. No further revision is being recommended.	Title: Decomposing the effect of women's educational status on fertility across the six geo- political zones in Nigeria: 2003-2018 Version: 4 Date: 12 Feb 2025 Reviewer: Elhakim Ibrahim Reviewer's report: All concerns raised in the previous submission had been addressed. No further revision is being recommended.	BMC	12905_2025_3636_ReviewerReport_V4_R3.pdf	{ "criticism": 1, "example": 0, "importance_and_relevance": 0, "materials_and_methods": 0, "praise": 0, "presentation_and_reporting": 0, "results_and_discussion": 0, "suggestion_and_solution": 1, "total": 2 }	{ "criticism": 0.5, "example": 0, "importance_and_relevance": 0, "materials_and_methods": 0, "praise": 0, "presentation_and_reporting": 0, "results_and_discussion": 0, "suggestion_and_solution": 0.5 }	1	[ { "content": "Please review this paper.", "role": "user" }, { "content": "Title: Decomposing the effect of women's educational status on fertility across the six geo-\npolitical zones in Nigeria: 2003-2018\nVersion: 4 Date: 12 Feb 2025\nReviewer: Elhakim Ibrahim\nReviewer's report:\nAll concerns raised in the previous submission had been addressed. No further revision is being\nrecommended.", "role": "assistant" } ]	2,025
Review for 10.1186/s12905-025-03636-z	Reviewed - bmc_womens_health	Title: Decomposing the effect of women's educational status on fertility across the six geo- political zones in Nigeria: 2003-2018 Version: 5 Date: 21 Feb 2025 Reviewer: Elhakim Ibrahim Reviewer's report: No further revision required.	Title: Decomposing the effect of women's educational status on fertility across the six geo- political zones in Nigeria: 2003-2018 Version: 5 Date: 21 Feb 2025 Reviewer: Elhakim Ibrahim Reviewer's report: No further revision required.	BMC	12905_2025_3636_ReviewerReport_V5_R3.pdf	{ "criticism": 0, "example": 0, "importance_and_relevance": 0, "materials_and_methods": 0, "praise": 0, "presentation_and_reporting": 0, "results_and_discussion": 0, "suggestion_and_solution": 1, "total": 1 }	{ "criticism": 0, "example": 0, "importance_and_relevance": 0, "materials_and_methods": 0, "praise": 0, "presentation_and_reporting": 0, "results_and_discussion": 0, "suggestion_and_solution": 1 }	1	[ { "content": "Please review this paper.", "role": "user" }, { "content": "Title: Decomposing the effect of women's educational status on fertility across the six geo-\npolitical zones in Nigeria: 2003-2018\nVersion: 5 Date: 21 Feb 2025\nReviewer: Elhakim Ibrahim\nReviewer's report:\nNo further revision required.", "role": "assistant" } ]	2,025
Review for 10.1186/s12905-025-03636-z	Reviewed - bmc_womens_health	Title: Decomposing the effect of women's educational status on fertility across the six geo- political zones in Nigeria: 2003-2018 Version: 5 Date: 24 Feb 2025 Reviewer's report: All comments have been addressed satisfactorily. No further comments.	Title: Decomposing the effect of women's educational status on fertility across the six geo- political zones in Nigeria: 2003-2018 Version: 5 Date: 24 Feb 2025 Reviewer's report: All comments have been addressed satisfactorily. No further comments.	BMC	12905_2025_3636_ReviewerReport_V5_R2.pdf	{ "criticism": 0, "example": 0, "importance_and_relevance": 0, "materials_and_methods": 0, "praise": 0, "presentation_and_reporting": 0, "results_and_discussion": 0, "suggestion_and_solution": 0, "total": 2 }	{ "criticism": 0, "example": 0, "importance_and_relevance": 0, "materials_and_methods": 0, "praise": 0, "presentation_and_reporting": 0, "results_and_discussion": 0, "suggestion_and_solution": 0 }	0	[ { "content": "Please review this paper.", "role": "user" }, { "content": "Title: Decomposing the effect of women's educational status on fertility across the six geo-\npolitical zones in Nigeria: 2003-2018\nVersion: 5 Date: 24 Feb 2025\nReviewer's report:\nAll comments have been addressed satisfactorily. No further comments.", "role": "assistant" } ]	2,025
Review for 10.1186/s12905-025-03632-3	Reviewed - bmc_womens_health	Title: Pelvic peritoneal endometriosis is linked to the endometrial inflammatory profile: a prospective cohort study Version: 3 Date: 17 Jan 2025 Reviewer: Irene Iavarone Reviewer's report: I read with great interest the present Manuscript which falls within the aim of the Journal. In my honest opinion, the topic is interesting enough to attract the readers’ attention. Methodology is accurate and conclusions are supported by the data analysis. Nevertheless, authors should clarify some points and improve the discussion citing relevant and novel key articles about the topic. For all those reasons, I suggested performing the minor revisions. - Inclusion criteria number II and III should be included in the exclusionary criteria; - In enrich the Discussion adding details upon potential treatment strategies deriving from the results of the study. Consider: "Cicinelli E, de Ziegler D, Vitagliano A. In women with endometriosis, effective treatment of chronic endometritis with antibiotics lowers serum CA-125 levels. Fertil Steril. 2024;121(6):1066-1068. doi:10.1016/j.fertnstert.2024.02.041"; - Authors may parallel their findings with other diagnostic biomarkers in endometriosis, as extracellular vesicles. Please see: "Ronsini C, Fumiento P, Iavarone I, Greco PF, Cobellis L, De Franciscis P. Liquid Biopsy in Endometriosis: A Systematic Review. Int J Mol Sci. 2023;24(7):6116. Published 2023 Mar 24. doi:10.3390/ijms24076116"; - Authors have not adequately highlighted the strength of the study. I suggest better specifying that point.	Title: Pelvic peritoneal endometriosis is linked to the endometrial inflammatory profile: a prospective cohort study Version: 3 Date: 17 Jan 2025 Reviewer: Irene Iavarone Reviewer's report: I read with great interest the present Manuscript which falls within the aim of the Journal. In my honest opinion, the topic is interesting enough to attract the readers’ attention. Methodology is accurate and conclusions are supported by the data analysis. Nevertheless, authors should clarify some points and improve the discussion citing relevant and novel key articles about the topic. For all those reasons, I suggested performing the minor revisions. - Inclusion criteria number II and III should be included in the exclusionary criteria; - In enrich the Discussion adding details upon potential treatment strategies deriving from the results of the study. Consider: "Cicinelli E, de Ziegler D, Vitagliano A. In women with endometriosis, effective treatment of chronic endometritis with antibiotics lowers serum CA-125 levels. Fertil Steril. 2024;121(6):1066-1068. doi:10.1016/j.fertnstert.2024.02.041"; - Authors may parallel their findings with other diagnostic biomarkers in endometriosis, as extracellular vesicles. Please see: "Ronsini C, Fumiento P, Iavarone I, Greco PF, Cobellis L, De Franciscis P. Liquid Biopsy in Endometriosis: A Systematic Review. Int J Mol Sci. 2023;24(7):6116. Published 2023 Mar 24. doi:10.3390/ijms24076116"; - Authors have not adequately highlighted the strength of the study. I suggest better specifying that point.	BMC	12905_2025_3632_ReviewerReport_V3_R1.pdf	{ "criticism": 1, "example": 1, "importance_and_relevance": 1, "materials_and_methods": 4, "praise": 3, "presentation_and_reporting": 3, "results_and_discussion": 4, "suggestion_and_solution": 5, "total": 15 }	{ "criticism": 0.06666666666666667, "example": 0.06666666666666667, "importance_and_relevance": 0.06666666666666667, "materials_and_methods": 0.26666666666666666, "praise": 0.2, "presentation_and_reporting": 0.2, "results_and_discussion": 0.26666666666666666, "suggestion_and_solution": 0.3333333333333333 }	1.466667	[ { "content": "Please review this paper.", "role": "user" }, { "content": "Title: Pelvic peritoneal endometriosis is linked to the endometrial inflammatory profile: a\nprospective cohort study\nVersion: 3 Date: 17 Jan 2025\nReviewer: Irene Iavarone\nReviewer's report:\nI read with great interest the present Manuscript which falls within the aim of the Journal. In my\nhonest opinion, the topic is interesting enough to attract the readers’ attention. Methodology is\naccurate and conclusions are supported by the data analysis. Nevertheless, authors should clarify\nsome points and improve the discussion citing relevant and novel key articles about the topic.\nFor all those reasons, I suggested performing the minor revisions.\n- Inclusion criteria number II and III should be included in the exclusionary criteria;\n- In enrich the Discussion adding details upon potential treatment strategies deriving from\nthe results of the study. Consider: \"Cicinelli E, de Ziegler D, Vitagliano A. In women with\nendometriosis, effective treatment of chronic endometritis with antibiotics lowers serum CA-125\nlevels. Fertil Steril. 2024;121(6):1066-1068. doi:10.1016/j.fertnstert.2024.02.041\";\n- Authors may parallel their findings with other diagnostic biomarkers in endometriosis, as\nextracellular vesicles. Please see: \"Ronsini C, Fumiento P, Iavarone I, Greco PF, Cobellis\nL, De Franciscis P. Liquid Biopsy in Endometriosis: A Systematic Review. Int J Mol Sci.\n2023;24(7):6116. Published 2023 Mar 24. doi:10.3390/ijms24076116\";\n- Authors have not adequately highlighted the strength of the study. I suggest better specifying\nthat point.", "role": "assistant" } ]	2,025
Review for 10.1186/s12905-025-03632-3	Reviewed - bmc_womens_health	Title: Pelvic peritoneal endometriosis is linked to the endometrial inflammatory profile: a prospective cohort study Version: 3 Date: 20 Jan 2025 Reviewer's report:	Title: Pelvic peritoneal endometriosis is linked to the endometrial inflammatory profile: a prospective cohort study Version: 3 Date: 20 Jan 2025 Reviewer's report:	BMC	12905_2025_3632_ReviewerReport_V3_R2.pdf	{ "criticism": 0, "example": 0, "importance_and_relevance": 0, "materials_and_methods": 0, "praise": 0, "presentation_and_reporting": 0, "results_and_discussion": 0, "suggestion_and_solution": 0, "total": 1 }	{ "criticism": 0, "example": 0, "importance_and_relevance": 0, "materials_and_methods": 0, "praise": 0, "presentation_and_reporting": 0, "results_and_discussion": 0, "suggestion_and_solution": 0 }	0	[ { "content": "Please review this paper.", "role": "user" }, { "content": "Title: Pelvic peritoneal endometriosis is linked to the endometrial inflammatory profile: a\nprospective cohort study\nVersion: 3 Date: 20 Jan 2025\nReviewer's report:", "role": "assistant" } ]	2,025
Review for 10.1186/s12905-025-03623-4	Reviewed - bmc_womens_health	Title: Factors Influencing Surgical Anxiety and Postoperative Pain: A Comprehensive Evaluation of Psychological and Gynecological Determinants Version: 1 Date: 05 Dec 2024 Reviewer's report: General Comments The manuscript explores an essential topic in perioperative care, highlighting the interaction between psychological and clinical factors in predicting surgical anxiety and postoperative pain in gynecological surgery. The study is comprehensive, employing validated tools and advanced statistical methods, providing robust insights into this multifaceted issue. However, the manuscript would benefit from improved clarity in data interpretation, enhanced discussion on practical implications, and addressing a few methodological limitations. Comments Please discuss on central sensitization and its impact on both phenomena DOI 10.1016/ j.jmig.2022.10.007 Clinical Implications: While the study identifies anxiety-specific patterns, practical recommendations for intervention (e.g., preoperative counseling strategies) are underdeveloped. More actionable insights would enhance the manuscript's utility. Discussion Depth: The comparison with existing studies (e.g., Baagil et al., Dibabu et al.) is relevant but should expand on differing methodologies or demographics that may account for discrepancies.	Title: Factors Influencing Surgical Anxiety and Postoperative Pain: A Comprehensive Evaluation of Psychological and Gynecological Determinants Version: 1 Date: 05 Dec 2024 Reviewer's report: General Comments The manuscript explores an essential topic in perioperative care, highlighting the interaction between psychological and clinical factors in predicting surgical anxiety and postoperative pain in gynecological surgery. The study is comprehensive, employing validated tools and advanced statistical methods, providing robust insights into this multifaceted issue. However, the manuscript would benefit from improved clarity in data interpretation, enhanced discussion on practical implications, and addressing a few methodological limitations. Comments Please discuss on central sensitization and its impact on both phenomena DOI 10.1016/ j.jmig.2022.10.007 Clinical Implications: While the study identifies anxiety-specific patterns, practical recommendations for intervention (e.g., preoperative counseling strategies) are underdeveloped. More actionable insights would enhance the manuscript's utility. Discussion Depth: The comparison with existing studies (e.g., Baagil et al., Dibabu et al.) is relevant but should expand on differing methodologies or demographics that may account for discrepancies.	BMC	12905_2025_3623_ReviewerReport_V1_R1.pdf	{ "criticism": 1, "example": 0, "importance_and_relevance": 3, "materials_and_methods": 3, "praise": 3, "presentation_and_reporting": 0, "results_and_discussion": 2, "suggestion_and_solution": 3, "total": 7 }	{ "criticism": 0.14285714285714285, "example": 0, "importance_and_relevance": 0.42857142857142855, "materials_and_methods": 0.42857142857142855, "praise": 0.42857142857142855, "presentation_and_reporting": 0, "results_and_discussion": 0.2857142857142857, "suggestion_and_solution": 0.42857142857142855 }	2.142857	[ { "content": "Please review this paper.", "role": "user" }, { "content": "Title: Factors Influencing Surgical Anxiety and Postoperative Pain: A Comprehensive\nEvaluation of Psychological and Gynecological Determinants\nVersion: 1 Date: 05 Dec 2024\nReviewer's report:\nGeneral Comments\nThe manuscript explores an essential topic in perioperative care, highlighting the interaction\nbetween psychological and clinical factors in predicting surgical anxiety and postoperative\npain in gynecological surgery. The study is comprehensive, employing validated tools and\nadvanced statistical methods, providing robust insights into this multifaceted issue. However,\nthe manuscript would benefit from improved clarity in data interpretation, enhanced discussion\non practical implications, and addressing a few methodological limitations.\nComments\nPlease discuss on central sensitization and its impact on both phenomena DOI 10.1016/\nj.jmig.2022.10.007\nClinical Implications: While the study identifies anxiety-specific patterns, practical\nrecommendations for intervention (e.g., preoperative counseling strategies) are underdeveloped.\nMore actionable insights would enhance the manuscript's utility.\nDiscussion Depth: The comparison with existing studies (e.g., Baagil et al., Dibabu et al.) is\nrelevant but should expand on differing methodologies or demographics that may account for\ndiscrepancies.", "role": "assistant" } ]	2,025
Review for 10.1186/s12905-025-03623-4	Reviewed - bmc_womens_health	Title: Factors Influencing Surgical Anxiety and Postoperative Pain: A Comprehensive Evaluation of Psychological and Gynecological Determinants Version: 1 Date: 02 Feb 2025 Reviewer's report: Dear Authors, I read your article investigating factors affecting postoperative pain and surgical anxiety. Here I highlight the main issues: - Introduction: it is well written and clear, effectively introducing into the subject of matter. However, where available, I'd rather shorten to make it more an introduction rather than a discussion in terms of length. - Materials and methods section: this section needs an overall improvement in terms of rigor and structure for reliability and reproducibility. I would suggest to follow a checklist (i.e. for observational studies: STROBE) to keep in mind every important section and subsection that needs to be included in the narration. - Selection criteria: not clear if you excluded patients with history of hysterectomy. - How was gynecological examination performed? Did it included also an ultrasound check? - "These conditions encompassed the presence of endometriosis, adenomyosis, leiomyoma (fibroids), endometrial polyps, and cesarean scar tissue". How can you affirm this before collecting data? - Results are difficult to read. Please include subsections according to the investigated outcomes. - I suggest to give a more pragmatical insight into some gynecological diseases probably increasing preoperative anxiety due their chronic course (endometriosis), or due to the different surgical approaches available in terms of uterine conservative surgery (leiomyoma). Regarding endometriosis, it is emerging that endo may affect pain perception thanks to central sensitisation (https://doi.org/10.1016/j.jmig.2022.10.007). Regarding leiomyoma, both open and minimally invasive techniques are available, and no clear indication is given for one over the other, despite being linked to different postoperative pain patterns (https://doi.org/10.3390/diagnostics14182046)	Title: Factors Influencing Surgical Anxiety and Postoperative Pain: A Comprehensive Evaluation of Psychological and Gynecological Determinants Version: 1 Date: 02 Feb 2025 Reviewer's report: Dear Authors, I read your article investigating factors affecting postoperative pain and surgical anxiety. Here I highlight the main issues: - Introduction: it is well written and clear, effectively introducing into the subject of matter. However, where available, I'd rather shorten to make it more an introduction rather than a discussion in terms of length. - Materials and methods section: this section needs an overall improvement in terms of rigor and structure for reliability and reproducibility. I would suggest to follow a checklist (i.e. for observational studies: STROBE) to keep in mind every important section and subsection that needs to be included in the narration. - Selection criteria: not clear if you excluded patients with history of hysterectomy. - How was gynecological examination performed? Did it included also an ultrasound check? - "These conditions encompassed the presence of endometriosis, adenomyosis, leiomyoma (fibroids), endometrial polyps, and cesarean scar tissue". How can you affirm this before collecting data? - Results are difficult to read. Please include subsections according to the investigated outcomes. - I suggest to give a more pragmatical insight into some gynecological diseases probably increasing preoperative anxiety due their chronic course (endometriosis), or due to the different surgical approaches available in terms of uterine conservative surgery (leiomyoma). Regarding endometriosis, it is emerging that endo may affect pain perception thanks to central sensitisation (https://doi.org/10.1016/j.jmig.2022.10.007). Regarding leiomyoma, both open and minimally invasive techniques are available, and no clear indication is given for one over the other, despite being linked to different postoperative pain patterns (https://doi.org/10.3390/diagnostics14182046)	BMC	12905_2025_3623_ReviewerReport_V1_R4.pdf	{ "criticism": 3, "example": 0, "importance_and_relevance": 1, "materials_and_methods": 7, "praise": 1, "presentation_and_reporting": 6, "results_and_discussion": 3, "suggestion_and_solution": 6, "total": 16 }	{ "criticism": 0.1875, "example": 0, "importance_and_relevance": 0.0625, "materials_and_methods": 0.4375, "praise": 0.0625, "presentation_and_reporting": 0.375, "results_and_discussion": 0.1875, "suggestion_and_solution": 0.375 }	1.6875	[ { "content": "Please review this paper.", "role": "user" }, { "content": "Title: Factors Influencing Surgical Anxiety and Postoperative Pain: A Comprehensive\nEvaluation of Psychological and Gynecological Determinants\nVersion: 1 Date: 02 Feb 2025\nReviewer's report:\nDear Authors,\nI read your article investigating factors affecting postoperative pain and surgical anxiety.\nHere I highlight the main issues:\n- Introduction: it is well written and clear, effectively introducing into the subject of matter.\nHowever, where available, I'd rather shorten to make it more an introduction rather than a\ndiscussion in terms of length.\n- Materials and methods section: this section needs an overall improvement in terms of rigor\nand structure for reliability and reproducibility. I would suggest to follow a checklist (i.e. for\nobservational studies: STROBE) to keep in mind every important section and subsection that\nneeds to be included in the narration.\n- Selection criteria: not clear if you excluded patients with history of hysterectomy.\n- How was gynecological examination performed? Did it included also an ultrasound check?\n- \"These conditions encompassed the presence of endometriosis, adenomyosis, leiomyoma\n(fibroids), endometrial polyps, and cesarean scar tissue\". How can you affirm this before\ncollecting data?\n- Results are difficult to read. Please include subsections according to the investigated outcomes.\n- I suggest to give a more pragmatical insight into some gynecological diseases probably\nincreasing preoperative anxiety due their chronic course (endometriosis), or due to the different\nsurgical approaches available in terms of uterine conservative surgery (leiomyoma).\nRegarding endometriosis, it is emerging that endo may affect pain perception thanks to central\nsensitisation (https://doi.org/10.1016/j.jmig.2022.10.007).\nRegarding leiomyoma, both open and minimally invasive techniques are available, and no clear\nindication is given for one over the other, despite being linked to different postoperative pain\npatterns (https://doi.org/10.3390/diagnostics14182046)", "role": "assistant" } ]	2,025
Review for 10.1186/s12905-025-03625-2	Reviewed - bmc_womens_health	Title: Global prevalence of sexual dysfunction in women with skin diseases: a systematic review and meta-analysis Version: 1 Date: 23 Nov 2024 Reviewer: Ehsan Amini-Salehi Reviewer's report: Dear Editor, Thank you for inviting me to review the manuscript titled "Global prevalence of sexual dysfunction in women with skin diseases: a systematic review and meta-analysis." The authors have conducted a systematic review and meta-analysis addressing a clinically relevant topic, particularly given the psychological and quality-of-life burdens associated with skin diseases. The study provides valuable insights into the global prevalence of female sexual dysfunction (FSD) across different dermatological conditions, and its findings have potential implications for patient care and policy-making. Below, I provide detailed comments categorized into clinical and statistical/methodological aspects. ________________________________________ Clinical Comments: 1. Scope of Diseases: While the manuscript includes a range of dermatological conditions, some less common disorders like keratosis pilaris and lichen planus are given substantial weight in the results. Clarify why these conditions were included despite their relatively small sample sizes and limited global burden. 2. Psychological Implications: The discussion could elaborate more on how psychological interventions, such as counseling or psychotherapy, can mitigate the impact of FSD in patients with skin diseases. 3. Impact of Disease Severity: While prevalence rates are provided, the study does not sufficiently differentiate between mild and severe cases of skin diseases. This distinction could provide more actionable insights for clinicians. 4. Cultural and Regional Variations: The manuscript notes that a majority of the studies are from Egypt and other specific regions. Discuss how cultural perceptions of skin diseases and sexual health might influence the reported prevalence rates. 5. Potential Interventions: Highlight the potential for multidisciplinary approaches (e.g., collaboration between dermatologists, psychologists, and gynecologists) to address FSD in women with skin diseases. 6. Assessment Tools: The discussion should compare the effectiveness and limitations of the various tools (e.g., FSFI, DLQI, ASEX) used to assess FSD in different studies, as these might affect the reported prevalence rates. 7. Vitiligo-Specific Insights: Since vitiligo had the highest reported prevalence of FSD, explore possible mechanisms beyond physical appearance concerns, such as oxidative stress or immune dysregulation, that may contribute to sexual dysfunction. 8. Role of Comorbidities: Discuss the role of common comorbidities like depression, anxiety, or metabolic disorders in amplifying the prevalence of FSD in women with skin diseases. 9. Practical Recommendations: Provide more specific recommendations for healthcare providers on screening for FSD in dermatological clinics. 10. Future Research Directions: The manuscript would benefit from a section on gaps in the current literature, such as the need for longitudinal studies to assess causality between skin diseases and FSD. Statistical and Methodological Comments: 1. Heterogeneity Management: The manuscript reports substantial heterogeneity in several analyses (e.g., I² > 90%). Provide more detailed explanations of how this heterogeneity was addressed and its potential impact on the robustness of the findings. 2. Subgroup Analyses: The subgroup analyses based on continents and tools used are informative. However, discuss whether these differences are statistically significant and if they affect the generalizability of the findings. 3. Publication Bias: While Begg and Mazumdar’s test indicated no significant publication bias, consider including a trim-and-fill analysis to validate this conclusion further. 4. Quality Assessment Transparency: The manuscript references the STROBE checklist for quality assessment but does not provide a summary table of the quality scores for the included studies. Adding this would enhance transparency. 5. Fixed vs. Random Effects: The results of both fixed and random-effects models are presented. Explain why the random-effects model was ultimately chosen for the primary analysis, particularly in light of the high heterogeneity. General Suggestions: • Improve figure legends for forest plots and subgroup analyses to make them more reader- friendly. • Include a supplementary table summarizing the characteristics of the included studies, particularly focusing on assessment tools and prevalence rates. • Ensure consistent terminology throughout the manuscript (e.g., FSD vs. sexual dysfunction). • Expand the limitations section to address the exclusion of non-English studies and potential biases in the selection process. I appreciate the opportunity to review this manuscript and hope these comments will help the authors refine their work. Best regards	Title: Global prevalence of sexual dysfunction in women with skin diseases: a systematic review and meta-analysis Version: 1 Date: 23 Nov 2024 Reviewer: Ehsan Amini-Salehi Reviewer's report: Dear Editor, Thank you for inviting me to review the manuscript titled "Global prevalence of sexual dysfunction in women with skin diseases: a systematic review and meta-analysis." The authors have conducted a systematic review and meta-analysis addressing a clinically relevant topic, particularly given the psychological and quality-of-life burdens associated with skin diseases. The study provides valuable insights into the global prevalence of female sexual dysfunction (FSD) across different dermatological conditions, and its findings have potential implications for patient care and policy-making. Below, I provide detailed comments categorized into clinical and statistical/methodological aspects. ________________________________________ Clinical Comments: 1. Scope of Diseases: While the manuscript includes a range of dermatological conditions, some less common disorders like keratosis pilaris and lichen planus are given substantial weight in the results. Clarify why these conditions were included despite their relatively small sample sizes and limited global burden. 2. Psychological Implications: The discussion could elaborate more on how psychological interventions, such as counseling or psychotherapy, can mitigate the impact of FSD in patients with skin diseases. 3. Impact of Disease Severity: While prevalence rates are provided, the study does not sufficiently differentiate between mild and severe cases of skin diseases. This distinction could provide more actionable insights for clinicians. 4. Cultural and Regional Variations: The manuscript notes that a majority of the studies are from Egypt and other specific regions. Discuss how cultural perceptions of skin diseases and sexual health might influence the reported prevalence rates. 5. Potential Interventions: Highlight the potential for multidisciplinary approaches (e.g., collaboration between dermatologists, psychologists, and gynecologists) to address FSD in women with skin diseases. 6. Assessment Tools: The discussion should compare the effectiveness and limitations of the various tools (e.g., FSFI, DLQI, ASEX) used to assess FSD in different studies, as these might affect the reported prevalence rates. 7. Vitiligo-Specific Insights: Since vitiligo had the highest reported prevalence of FSD, explore possible mechanisms beyond physical appearance concerns, such as oxidative stress or immune dysregulation, that may contribute to sexual dysfunction. 8. Role of Comorbidities: Discuss the role of common comorbidities like depression, anxiety, or metabolic disorders in amplifying the prevalence of FSD in women with skin diseases. 9. Practical Recommendations: Provide more specific recommendations for healthcare providers on screening for FSD in dermatological clinics. 10. Future Research Directions: The manuscript would benefit from a section on gaps in the current literature, such as the need for longitudinal studies to assess causality between skin diseases and FSD. Statistical and Methodological Comments: 1. Heterogeneity Management: The manuscript reports substantial heterogeneity in several analyses (e.g., I² > 90%). Provide more detailed explanations of how this heterogeneity was addressed and its potential impact on the robustness of the findings. 2. Subgroup Analyses: The subgroup analyses based on continents and tools used are informative. However, discuss whether these differences are statistically significant and if they affect the generalizability of the findings. 3. Publication Bias: While Begg and Mazumdar’s test indicated no significant publication bias, consider including a trim-and-fill analysis to validate this conclusion further. 4. Quality Assessment Transparency: The manuscript references the STROBE checklist for quality assessment but does not provide a summary table of the quality scores for the included studies. Adding this would enhance transparency. 5. Fixed vs. Random Effects: The results of both fixed and random-effects models are presented. Explain why the random-effects model was ultimately chosen for the primary analysis, particularly in light of the high heterogeneity. General Suggestions: • Improve figure legends for forest plots and subgroup analyses to make them more reader- friendly. • Include a supplementary table summarizing the characteristics of the included studies, particularly focusing on assessment tools and prevalence rates. • Ensure consistent terminology throughout the manuscript (e.g., FSD vs. sexual dysfunction). • Expand the limitations section to address the exclusion of non-English studies and potential biases in the selection process. I appreciate the opportunity to review this manuscript and hope these comments will help the authors refine their work. Best regards	BMC	12905_2025_3625_ReviewerReport_V1_R1.pdf	{ "criticism": 2, "example": 0, "importance_and_relevance": 8, "materials_and_methods": 18, "praise": 4, "presentation_and_reporting": 5, "results_and_discussion": 9, "suggestion_and_solution": 18, "total": 47 }	{ "criticism": 0.0425531914893617, "example": 0, "importance_and_relevance": 0.1702127659574468, "materials_and_methods": 0.3829787234042553, "praise": 0.0851063829787234, "presentation_and_reporting": 0.10638297872340426, "results_and_discussion": 0.19148936170212766, "suggestion_and_solution": 0.3829787234042553 }	1.361702	[ { "content": "Please review this paper.", "role": "user" }, { "content": "Title: Global prevalence of sexual dysfunction in women with skin diseases: a systematic review\nand meta-analysis\nVersion: 1 Date: 23 Nov 2024\nReviewer: Ehsan Amini-Salehi\nReviewer's report:\nDear Editor,\nThank you for inviting me to review the manuscript titled \"Global prevalence of sexual\ndysfunction in women with skin diseases: a systematic review and meta-analysis.\" The authors\nhave conducted a systematic review and meta-analysis addressing a clinically relevant topic,\nparticularly given the psychological and quality-of-life burdens associated with skin diseases.\nThe study provides valuable insights into the global prevalence of female sexual dysfunction\n(FSD) across different dermatological conditions, and its findings have potential implications\nfor patient care and policy-making. Below, I provide detailed comments categorized into clinical\nand statistical/methodological aspects.\n________________________________________\nClinical Comments:\n1. Scope of Diseases: While the manuscript includes a range of dermatological conditions, some\nless common disorders like keratosis pilaris and lichen planus are given substantial weight in the\nresults. Clarify why these conditions were included despite their relatively small sample sizes\nand limited global burden.\n2. Psychological Implications: The discussion could elaborate more on how psychological\ninterventions, such as counseling or psychotherapy, can mitigate the impact of FSD in patients\nwith skin diseases.\n3. Impact of Disease Severity: While prevalence rates are provided, the study does not\nsufficiently differentiate between mild and severe cases of skin diseases. This distinction could\nprovide more actionable insights for clinicians.\n4. Cultural and Regional Variations: The manuscript notes that a majority of the studies are from\nEgypt and other specific regions. Discuss how cultural perceptions of skin diseases and sexual\nhealth might influence the reported prevalence rates.\n5. Potential Interventions: Highlight the potential for multidisciplinary approaches (e.g.,\ncollaboration between dermatologists, psychologists, and gynecologists) to address FSD in\nwomen with skin diseases.\n6. Assessment Tools: The discussion should compare the effectiveness and limitations of the\nvarious tools (e.g., FSFI, DLQI, ASEX) used to assess FSD in different studies, as these might\naffect the reported prevalence rates.\n7. Vitiligo-Specific Insights: Since vitiligo had the highest reported prevalence of FSD, explore\npossible mechanisms beyond physical appearance concerns, such as oxidative stress or immune\ndysregulation, that may contribute to sexual dysfunction.\n8. Role of Comorbidities: Discuss the role of common comorbidities like depression, anxiety,\nor metabolic disorders in amplifying the prevalence of FSD in women with skin diseases.\n9. Practical Recommendations: Provide more specific recommendations for healthcare providers\non screening for FSD in dermatological clinics.\n10. Future Research Directions: The manuscript would benefit from a section on gaps in the\ncurrent literature, such as the need for longitudinal studies to assess causality between skin\ndiseases and FSD.\nStatistical and Methodological Comments:\n1. Heterogeneity Management: The manuscript reports substantial heterogeneity in several\nanalyses (e.g., I² > 90%). Provide more detailed explanations of how this heterogeneity was\naddressed and its potential impact on the robustness of the findings.\n2. Subgroup Analyses: The subgroup analyses based on continents and tools used are\ninformative. However, discuss whether these differences are statistically significant and if they\naffect the generalizability of the findings.\n3. Publication Bias: While Begg and Mazumdar’s test indicated no significant publication bias,\nconsider including a trim-and-fill analysis to validate this conclusion further.\n4. Quality Assessment Transparency: The manuscript references the STROBE checklist for\nquality assessment but does not provide a summary table of the quality scores for the included\nstudies. Adding this would enhance transparency.\n5. Fixed vs. Random Effects: The results of both fixed and random-effects models are presented.\nExplain why the random-effects model was ultimately chosen for the primary analysis,\nparticularly in light of the high heterogeneity.\nGeneral Suggestions:\n• Improve figure legends for forest plots and subgroup analyses to make them more reader-\nfriendly.\n• Include a supplementary table summarizing the characteristics of the included studies,\nparticularly focusing on assessment tools and prevalence rates.\n• Ensure consistent terminology throughout the manuscript (e.g., FSD vs. sexual dysfunction).\n• Expand the limitations section to address the exclusion of non-English studies and potential\nbiases in the selection process.\nI appreciate the opportunity to review this manuscript and hope these comments will help the\nauthors refine their work.\nBest regards", "role": "assistant" } ]	2,025
Review for 10.1186/s12905-025-03625-2	Reviewed - bmc_womens_health	Title: Global prevalence of sexual dysfunction in women with skin diseases: a systematic review and meta-analysis Version: 1 Date: 26 Nov 2024 Reviewer's report: This systematic review and meta-analysis investigated the global prevalence of FSD among women with skin diseases, analyzing data from 24 studies encompassing 45 datasets, and revealed a substantial overall FSD prevalence of 61.3% across various dermatological conditions, with notably higher rates in specific conditions such as vitiligo, psoriasis, and hidradenitis suppurative. This article has the following shortcomings# 1. The authors state that 'the search process was repeated in late April 2024'. If an updated search was conducted, please specify the rationale, any new findings, and their impact on the results. 2. The inclusion and exclusion criteria need refinement, particularly regarding the definition of FSD. The authors should specify which diagnostic criteria and assessment tools were considered valid for FSD evaluation in their analysis. 3. The statistical analysis section requires more detail. Please provide essential information about the meta-analytic methods, including the model selection rationale, heterogeneity assessment approach, and sensitivity analysis procedures. 4. Please provide specific reasons for article exclusion in the PRISMA flow diagram after full- text assessment. 5. In Figure 7, the first graph appears to be inverted. 6. Please explain the rationale for only including vitiligo, psoriasis, and hidradenitis suppurativa in this study. Why were other common dermatological conditions such as atopic dermatitis, urticaria, and acne not included in the analysis? 7. The Discussion section would benefit from a more in-depth exploration of the potential mechanisms linking skin conditions to FSD. 8. While the systematic review provides comprehensive data analysis on the relationship between dermatological conditions and female sexual dysfunction, it falls short in addressing the crucial 'so what' question. As a systematic review should ultimately guide clinical practice, please elaborate on the practical implications of these findings. Specifically, how should these results inform dermatologists' daily practice? A clear discussion of these practical applications would significantly enhance the clinical utility of this review. 9. In the manuscript, it states 'FSFI tool reporting a prevalence of 77.1% (95% CI: 61.3% - 87.7%)', however, in Table 5, the lower limit is shown as 0.612. This inconsistency needs to be addressed. Please thoroughly check and verify the accuracy of all numerical data throughout the manuscript to ensure consistency and precision. 10. The overall language and writing quality of the manuscript needs improvement.	Title: Global prevalence of sexual dysfunction in women with skin diseases: a systematic review and meta-analysis Version: 1 Date: 26 Nov 2024 Reviewer's report: This systematic review and meta-analysis investigated the global prevalence of FSD among women with skin diseases, analyzing data from 24 studies encompassing 45 datasets, and revealed a substantial overall FSD prevalence of 61.3% across various dermatological conditions, with notably higher rates in specific conditions such as vitiligo, psoriasis, and hidradenitis suppurative. This article has the following shortcomings# 1. The authors state that 'the search process was repeated in late April 2024'. If an updated search was conducted, please specify the rationale, any new findings, and their impact on the results. 2. The inclusion and exclusion criteria need refinement, particularly regarding the definition of FSD. The authors should specify which diagnostic criteria and assessment tools were considered valid for FSD evaluation in their analysis. 3. The statistical analysis section requires more detail. Please provide essential information about the meta-analytic methods, including the model selection rationale, heterogeneity assessment approach, and sensitivity analysis procedures. 4. Please provide specific reasons for article exclusion in the PRISMA flow diagram after full- text assessment. 5. In Figure 7, the first graph appears to be inverted. 6. Please explain the rationale for only including vitiligo, psoriasis, and hidradenitis suppurativa in this study. Why were other common dermatological conditions such as atopic dermatitis, urticaria, and acne not included in the analysis? 7. The Discussion section would benefit from a more in-depth exploration of the potential mechanisms linking skin conditions to FSD. 8. While the systematic review provides comprehensive data analysis on the relationship between dermatological conditions and female sexual dysfunction, it falls short in addressing the crucial 'so what' question. As a systematic review should ultimately guide clinical practice, please elaborate on the practical implications of these findings. Specifically, how should these results inform dermatologists' daily practice? A clear discussion of these practical applications would significantly enhance the clinical utility of this review. 9. In the manuscript, it states 'FSFI tool reporting a prevalence of 77.1% (95% CI: 61.3% - 87.7%)', however, in Table 5, the lower limit is shown as 0.612. This inconsistency needs to be addressed. Please thoroughly check and verify the accuracy of all numerical data throughout the manuscript to ensure consistency and precision. 10. The overall language and writing quality of the manuscript needs improvement.	BMC	12905_2025_3625_ReviewerReport_V1_R3.pdf	{ "criticism": 2, "example": 1, "importance_and_relevance": 3, "materials_and_methods": 14, "praise": 3, "presentation_and_reporting": 10, "results_and_discussion": 5, "suggestion_and_solution": 13, "total": 30 }	{ "criticism": 0.06666666666666667, "example": 0.03333333333333333, "importance_and_relevance": 0.1, "materials_and_methods": 0.4666666666666667, "praise": 0.1, "presentation_and_reporting": 0.3333333333333333, "results_and_discussion": 0.16666666666666666, "suggestion_and_solution": 0.43333333333333335 }	1.7	[ { "content": "Please review this paper.", "role": "user" }, { "content": "Title: Global prevalence of sexual dysfunction in women with skin diseases: a systematic review\nand meta-analysis\nVersion: 1 Date: 26 Nov 2024\nReviewer's report:\nThis systematic review and meta-analysis investigated the global prevalence of FSD among\nwomen with skin diseases, analyzing data from 24 studies encompassing 45 datasets, and\nrevealed a substantial overall FSD prevalence of 61.3% across various dermatological\nconditions, with notably higher rates in specific conditions such as vitiligo, psoriasis, and\nhidradenitis suppurative. This article has the following shortcomings#\n1. The authors state that 'the search process was repeated in late April 2024'. If an updated search\nwas conducted, please specify the rationale, any new findings, and their impact on the results.\n2. The inclusion and exclusion criteria need refinement, particularly regarding the definition of\nFSD. The authors should specify which diagnostic criteria and assessment tools were considered\nvalid for FSD evaluation in their analysis.\n3. The statistical analysis section requires more detail. Please provide essential information about\nthe meta-analytic methods, including the model selection rationale, heterogeneity assessment\napproach, and sensitivity analysis procedures.\n4. Please provide specific reasons for article exclusion in the PRISMA flow diagram after full-\ntext assessment.\n5. In Figure 7, the first graph appears to be inverted.\n6. Please explain the rationale for only including vitiligo, psoriasis, and hidradenitis suppurativa\nin this study. Why were other common dermatological conditions such as atopic dermatitis,\nurticaria, and acne not included in the analysis?\n7. The Discussion section would benefit from a more in-depth exploration of the potential\nmechanisms linking skin conditions to FSD.\n8. While the systematic review provides comprehensive data analysis on the relationship\nbetween dermatological conditions and female sexual dysfunction, it falls short in addressing\nthe crucial 'so what' question. As a systematic review should ultimately guide clinical practice,\nplease elaborate on the practical implications of these findings. Specifically, how should these\nresults inform dermatologists' daily practice? A clear discussion of these practical applications\nwould significantly enhance the clinical utility of this review.\n9. In the manuscript, it states 'FSFI tool reporting a prevalence of 77.1% (95% CI: 61.3% -\n87.7%)', however, in Table 5, the lower limit is shown as 0.612. This inconsistency needs to be\naddressed. Please thoroughly check and verify the accuracy of all numerical data throughout the\nmanuscript to ensure consistency and precision.\n10. The overall language and writing quality of the manuscript needs improvement.", "role": "assistant" } ]	2,025
Review for 10.1186/s12905-025-03625-2	Reviewed - bmc_womens_health	Title: Global prevalence of sexual dysfunction in women with skin diseases: a systematic review and meta-analysis Version: 1 Date: 27 Nov 2024 Reviewer's report: Very interesting article that studies the impact of common dermatosis on women’s sexual life. In this regard, I believe that the impact of atopic dermatitis on this topic has not been fully addressed. Eczema, causing chronic damage to the skin barrier, can have a significant impact on sexuality, especially when localized to the genital areas. In this respect, we invite the authors to discuss the following article that analyzes precisely this topic and also studies the influence of dupilumab on improving the sexual sphere in subjects suffering from atopic dermatitis: - Napolitano M, Fabbrocini G, Kastl S, Battista T, Di Guida A, Martora F, Picone V, Ventura V, Patruno C. Effect of Dupilumab on Sexual Desire in Adult Patients with Moderate to Severe Atopic Dermatitis. Medicina (Kaunas). 2022 Nov 23;58(12):1708. doi: 10.3390/ medicina58121708. PMID: 36556910; PMCID: PMC9782472. Finally I also suggest a revision of the English language in the article.	Title: Global prevalence of sexual dysfunction in women with skin diseases: a systematic review and meta-analysis Version: 1 Date: 27 Nov 2024 Reviewer's report: Very interesting article that studies the impact of common dermatosis on women’s sexual life. In this regard, I believe that the impact of atopic dermatitis on this topic has not been fully addressed. Eczema, causing chronic damage to the skin barrier, can have a significant impact on sexuality, especially when localized to the genital areas. In this respect, we invite the authors to discuss the following article that analyzes precisely this topic and also studies the influence of dupilumab on improving the sexual sphere in subjects suffering from atopic dermatitis: - Napolitano M, Fabbrocini G, Kastl S, Battista T, Di Guida A, Martora F, Picone V, Ventura V, Patruno C. Effect of Dupilumab on Sexual Desire in Adult Patients with Moderate to Severe Atopic Dermatitis. Medicina (Kaunas). 2022 Nov 23;58(12):1708. doi: 10.3390/ medicina58121708. PMID: 36556910; PMCID: PMC9782472. Finally I also suggest a revision of the English language in the article.	BMC	12905_2025_3625_ReviewerReport_V1_R5.pdf	{ "criticism": 1, "example": 0, "importance_and_relevance": 2, "materials_and_methods": 1, "praise": 1, "presentation_and_reporting": 1, "results_and_discussion": 0, "suggestion_and_solution": 2, "total": 8 }	{ "criticism": 0.125, "example": 0, "importance_and_relevance": 0.25, "materials_and_methods": 0.125, "praise": 0.125, "presentation_and_reporting": 0.125, "results_and_discussion": 0, "suggestion_and_solution": 0.25 }	1	[ { "content": "Please review this paper.", "role": "user" }, { "content": "Title: Global prevalence of sexual dysfunction in women with skin diseases: a systematic review\nand meta-analysis\nVersion: 1 Date: 27 Nov 2024\nReviewer's report:\nVery interesting article that studies the impact of common dermatosis on women’s sexual life.\nIn this regard, I believe that the impact of atopic dermatitis on this topic has not been fully\naddressed. Eczema, causing chronic damage to the skin barrier, can have a significant impact\non sexuality, especially when localized to the genital areas. In this respect, we invite the authors\nto discuss the following article that analyzes precisely this topic and also studies the influence\nof dupilumab on improving the sexual sphere in subjects suffering from atopic dermatitis:\n- Napolitano M, Fabbrocini G, Kastl S, Battista T, Di Guida A, Martora F, Picone V,\nVentura V, Patruno C. Effect of Dupilumab on Sexual Desire in Adult Patients with Moderate\nto Severe Atopic Dermatitis. Medicina (Kaunas). 2022 Nov 23;58(12):1708. doi: 10.3390/\nmedicina58121708. PMID: 36556910; PMCID: PMC9782472.\nFinally I also suggest a revision of the English language in the article.", "role": "assistant" } ]	2,025
Review for 10.1186/s12905-025-03625-2	Reviewed - bmc_womens_health	Title: Global prevalence of sexual dysfunction in women with skin diseases: a systematic review and meta-analysis Version: 2 Date: 11 Feb 2025 Reviewer: Ehsan Amini-Salehi Reviewer's report: I have no further comments	Title: Global prevalence of sexual dysfunction in women with skin diseases: a systematic review and meta-analysis Version: 2 Date: 11 Feb 2025 Reviewer: Ehsan Amini-Salehi Reviewer's report: I have no further comments	BMC	12905_2025_3625_ReviewerReport_V2_R1.pdf	{ "criticism": 1, "example": 0, "importance_and_relevance": 0, "materials_and_methods": 1, "praise": 0, "presentation_and_reporting": 0, "results_and_discussion": 0, "suggestion_and_solution": 0, "total": 1 }	{ "criticism": 1, "example": 0, "importance_and_relevance": 0, "materials_and_methods": 1, "praise": 0, "presentation_and_reporting": 0, "results_and_discussion": 0, "suggestion_and_solution": 0 }	2	[ { "content": "Please review this paper.", "role": "user" }, { "content": "Title: Global prevalence of sexual dysfunction in women with skin diseases: a systematic review\nand meta-analysis\nVersion: 2 Date: 11 Feb 2025\nReviewer: Ehsan Amini-Salehi\nReviewer's report:\nI have no further comments", "role": "assistant" } ]	2,025
Review for 10.1186/s12905-025-03625-2	Reviewed - bmc_womens_health	Title: Global prevalence of sexual dysfunction in women with skin diseases: a systematic review and meta-analysis Version: 2 Date: 15 Feb 2025 Reviewer's report: I am satisfied with this revision.	Title: Global prevalence of sexual dysfunction in women with skin diseases: a systematic review and meta-analysis Version: 2 Date: 15 Feb 2025 Reviewer's report: I am satisfied with this revision.	BMC	12905_2025_3625_ReviewerReport_V2_R3.pdf	{ "criticism": 0, "example": 0, "importance_and_relevance": 0, "materials_and_methods": 1, "praise": 1, "presentation_and_reporting": 0, "results_and_discussion": 0, "suggestion_and_solution": 0, "total": 1 }	{ "criticism": 0, "example": 0, "importance_and_relevance": 0, "materials_and_methods": 1, "praise": 1, "presentation_and_reporting": 0, "results_and_discussion": 0, "suggestion_and_solution": 0 }	2	[ { "content": "Please review this paper.", "role": "user" }, { "content": "Title: Global prevalence of sexual dysfunction in women with skin diseases: a systematic review\nand meta-analysis\nVersion: 2 Date: 15 Feb 2025\nReviewer's report:\nI am satisfied with this revision.", "role": "assistant" } ]	2,025
Review for 10.1186/s12905-025-03605-6	Reviewed - bmc_womens_health	Title: Cranial Venous Sinus Thrombosis Following Early Spontaneous Abortion: A Case Report and Literature Review Version: 2 Date: 12 Mar 2024 Reviewer: Hari Prasad Kaphle Reviewer's report: Manuscript title: Cerebral Venous Sinus Thrombosis Following Early Spontaneous Abortion: A Case Report and Literature Review Overall The rare case with clinical importance professional of a related field The manuscript follows all the steps of case reporting The study was conducted as per current ethical practice Consent is also obtained from the patient Title The title is clear and concise. However, is it necessary to include “and Literature Review” in the title? Abstract The abstract is also clear and concise. However, in lines 18 and 19 “The patient achieved a favorable outcome after aggressive endovascular thrombectomy and direct catheter thrombolysis with urokinase” needs to be elaborate properly. What intervention you have provided? And the outcome achieved? Keywords Sufficient Keywords based on the MeSH terms Introduction Line no 50 “The patient had a good prognosis following aggressive treatment” is the part of conclusion. Is it necessary to include it in the introduction? Case description It’s better to describe the details of the case, including demography, assessment, findings, investigations, intervention detail, and treatment outcome separately in separate paragraphs. There is lacking characteristics of the first service point where the case is reported and when the case is reported. Discussion Discussed with adequate literature. Why this case is of clinical importance? And what are the limitations related to the case? If any, incorporate them into the discussion. Conclusion Conclusion massage for professionals in the same clinical setting is appropriate. Reference The font and font size of the references need to be corrected. Some references need to be corrected e.g. Reference numbers 22 and 27. In the “Title of the article,” all letters are capitalized. It's better to add DOI and hyperlink/cross-reference to all references. Thank you.	Title: Cranial Venous Sinus Thrombosis Following Early Spontaneous Abortion: A Case Report and Literature Review Version: 2 Date: 12 Mar 2024 Reviewer: Hari Prasad Kaphle Reviewer's report: Manuscript title: Cerebral Venous Sinus Thrombosis Following Early Spontaneous Abortion: A Case Report and Literature Review Overall The rare case with clinical importance professional of a related field The manuscript follows all the steps of case reporting The study was conducted as per current ethical practice Consent is also obtained from the patient Title The title is clear and concise. However, is it necessary to include “and Literature Review” in the title? Abstract The abstract is also clear and concise. However, in lines 18 and 19 “The patient achieved a favorable outcome after aggressive endovascular thrombectomy and direct catheter thrombolysis with urokinase” needs to be elaborate properly. What intervention you have provided? And the outcome achieved? Keywords Sufficient Keywords based on the MeSH terms Introduction Line no 50 “The patient had a good prognosis following aggressive treatment” is the part of conclusion. Is it necessary to include it in the introduction? Case description It’s better to describe the details of the case, including demography, assessment, findings, investigations, intervention detail, and treatment outcome separately in separate paragraphs. There is lacking characteristics of the first service point where the case is reported and when the case is reported. Discussion Discussed with adequate literature. Why this case is of clinical importance? And what are the limitations related to the case? If any, incorporate them into the discussion. Conclusion Conclusion massage for professionals in the same clinical setting is appropriate. Reference The font and font size of the references need to be corrected. Some references need to be corrected e.g. Reference numbers 22 and 27. In the “Title of the article,” all letters are capitalized. It's better to add DOI and hyperlink/cross-reference to all references. Thank you.	BMC	12905_2025_3605_ReviewerReport_V2_R2.pdf	{ "criticism": 1, "example": 2, "importance_and_relevance": 1, "materials_and_methods": 2, "praise": 5, "presentation_and_reporting": 11, "results_and_discussion": 5, "suggestion_and_solution": 9, "total": 21 }	{ "criticism": 0.047619047619047616, "example": 0.09523809523809523, "importance_and_relevance": 0.047619047619047616, "materials_and_methods": 0.09523809523809523, "praise": 0.23809523809523808, "presentation_and_reporting": 0.5238095238095238, "results_and_discussion": 0.23809523809523808, "suggestion_and_solution": 0.42857142857142855 }	1.714286	[ { "content": "Please review this paper.", "role": "user" }, { "content": "Title: Cranial Venous Sinus Thrombosis Following Early Spontaneous Abortion: A Case Report\nand Literature Review\nVersion: 2 Date: 12 Mar 2024\nReviewer: Hari Prasad Kaphle\nReviewer's report:\nManuscript title: Cerebral Venous Sinus Thrombosis Following Early Spontaneous Abortion:\nA Case Report and Literature Review\nOverall\nThe rare case with clinical importance professional of a related field\nThe manuscript follows all the steps of case reporting\nThe study was conducted as per current ethical practice\nConsent is also obtained from the patient\nTitle\nThe title is clear and concise. However, is it necessary to include “and Literature Review” in\nthe title?\nAbstract\nThe abstract is also clear and concise. However, in lines 18 and 19 “The patient\nachieved a favorable outcome after aggressive endovascular thrombectomy and direct catheter\nthrombolysis with urokinase” needs to be elaborate properly. What intervention you have\nprovided? And the outcome achieved?\nKeywords\nSufficient Keywords based on the MeSH terms\nIntroduction\nLine no 50 “The patient had a good prognosis following aggressive treatment” is the part of\nconclusion. Is it necessary to include it in the introduction?\nCase description\nIt’s better to describe the details of the case, including demography, assessment, findings,\ninvestigations, intervention detail, and treatment outcome separately in separate paragraphs.\nThere is lacking characteristics of the first service point where the case is reported and when\nthe case is reported.\nDiscussion\nDiscussed with adequate literature.\nWhy this case is of clinical importance? And what are the limitations related to the case? If any,\nincorporate them into the discussion.\nConclusion\nConclusion massage for professionals in the same clinical setting is appropriate.\nReference\nThe font and font size of the references need to be corrected.\nSome references need to be corrected e.g. Reference numbers 22 and 27. In the “Title of the\narticle,” all letters are capitalized.\nIt's better to add DOI and hyperlink/cross-reference to all references.\nThank you.", "role": "assistant" } ]	2,025
Review for 10.1186/s12905-025-03605-6	Reviewed - bmc_womens_health	Title: Cranial Venous Sinus Thrombosis Following Early Spontaneous Abortion: A Case Report and Literature Review Version: 2 Date: 09 Jun 2024 Reviewer's report: This case report on cerebral venous sinus thrombosis (CVST) following early spontaneous abortion extensively discusses the general epidemiology of CVST and its association with pregnancy. I have some comments for authors. Following the instructions for authors, the abstract should be organized with the subheadings “Background,” “Case Presentation,” and “Conclusion. There have been many reports of an association between pregnancy and CVST, but what is the extent of the association between abortion and CVST in past reports? In the present case report, it appears that having an abortion was associated with CVST, but the association between abortion and CVST remains unclear. Is it possible that CVST was complicated by an early pregnancy? It is important for this case report to consider the impact of abortion (rather than CVST associated with pregnancy) on CVST, using previous studies and other relevant information. It is emphasized that CVST in early pregnancy is rare, but what are some of the past reports? In the conclusion, the statement "For young patients with early pregnancy bleeding, comprehensive coagulation function and D-dimer tests should be conducted." seems overly emphatic for a case report. This is merely a single case report, and moreover, a rare one, which is insufficient to strongly recommend a specific testing or treatment approach. It is important to avoid conveying misleading messages to the readers.	Title: Cranial Venous Sinus Thrombosis Following Early Spontaneous Abortion: A Case Report and Literature Review Version: 2 Date: 09 Jun 2024 Reviewer's report: This case report on cerebral venous sinus thrombosis (CVST) following early spontaneous abortion extensively discusses the general epidemiology of CVST and its association with pregnancy. I have some comments for authors. Following the instructions for authors, the abstract should be organized with the subheadings “Background,” “Case Presentation,” and “Conclusion. There have been many reports of an association between pregnancy and CVST, but what is the extent of the association between abortion and CVST in past reports? In the present case report, it appears that having an abortion was associated with CVST, but the association between abortion and CVST remains unclear. Is it possible that CVST was complicated by an early pregnancy? It is important for this case report to consider the impact of abortion (rather than CVST associated with pregnancy) on CVST, using previous studies and other relevant information. It is emphasized that CVST in early pregnancy is rare, but what are some of the past reports? In the conclusion, the statement "For young patients with early pregnancy bleeding, comprehensive coagulation function and D-dimer tests should be conducted." seems overly emphatic for a case report. This is merely a single case report, and moreover, a rare one, which is insufficient to strongly recommend a specific testing or treatment approach. It is important to avoid conveying misleading messages to the readers.	BMC	12905_2025_3605_ReviewerReport_V2_R7.pdf	{ "criticism": 3, "example": 0, "importance_and_relevance": 1, "materials_and_methods": 2, "praise": 0, "presentation_and_reporting": 3, "results_and_discussion": 2, "suggestion_and_solution": 4, "total": 12 }	{ "criticism": 0.25, "example": 0, "importance_and_relevance": 0.08333333333333333, "materials_and_methods": 0.16666666666666666, "praise": 0, "presentation_and_reporting": 0.25, "results_and_discussion": 0.16666666666666666, "suggestion_and_solution": 0.3333333333333333 }	1.25	[ { "content": "Please review this paper.", "role": "user" }, { "content": "Title: Cranial Venous Sinus Thrombosis Following Early Spontaneous Abortion: A Case Report\nand Literature Review\nVersion: 2 Date: 09 Jun 2024\nReviewer's report:\nThis case report on cerebral venous sinus thrombosis (CVST) following early spontaneous\nabortion extensively discusses the general epidemiology of CVST and its association with\npregnancy.\nI have some comments for authors.\nFollowing the instructions for authors, the abstract should be organized with the subheadings\n“Background,” “Case Presentation,” and “Conclusion.\nThere have been many reports of an association between pregnancy and CVST, but what is the\nextent of the association between abortion and CVST in past reports?\nIn the present case report, it appears that having an abortion was associated with CVST, but\nthe association between abortion and CVST remains unclear. Is it possible that CVST was\ncomplicated by an early pregnancy? It is important for this case report to consider the impact of\nabortion (rather than CVST associated with pregnancy) on CVST, using previous studies and\nother relevant information.\nIt is emphasized that CVST in early pregnancy is rare, but what are some of the past reports?\nIn the conclusion, the statement \"For young patients with early pregnancy bleeding,\ncomprehensive coagulation function and D-dimer tests should be conducted.\" seems overly\nemphatic for a case report. This is merely a single case report, and moreover, a rare one, which\nis insufficient to strongly recommend a specific testing or treatment approach. It is important to\navoid conveying misleading messages to the readers.", "role": "assistant" } ]	2,025
Review for 10.1186/s12905-025-03605-6	Reviewed - bmc_womens_health	Title: Cranial Venous Sinus Thrombosis Following Early Spontaneous Abortion: A Case Report and Literature Review Version: 2 Date: 12 Jun 2024 Reviewer's report: Dear Editor, Thank you for the opportunity to review the article entitled "Cerebral Venous Sinus Thrombosis Following Early Spontaneous Abortion: A Case Report and Literature Review" for BMC Women's Health. The topic was fascinating, and I read the paper with great interest. However, I would like to mention some points: 1. The English language needs revision. 2. The information of the meta-analysis in the introduction can be summarized. Some replication of the symptoms can be found in the introduction and discussion. 3. The authors should elaborate more on the procedure of thrombectomy in the case report section. 4. The authors should mention the dose of heparin. 5. The normal range of laboratory findings should be added. 6. The duration of follow-up and evaluation should be mentioned. 7. The authors mentioned an association between the ChAdOx1 nCoV-19 vaccine and CVST; however, they did not mention the relation with the current case. The authors should mention if the patient received the same vaccine recently. 8. In general, the discussion can be summarized and be more related to the aforementioned patient’s status. 9. The table should be spell-checked.	Title: Cranial Venous Sinus Thrombosis Following Early Spontaneous Abortion: A Case Report and Literature Review Version: 2 Date: 12 Jun 2024 Reviewer's report: Dear Editor, Thank you for the opportunity to review the article entitled "Cerebral Venous Sinus Thrombosis Following Early Spontaneous Abortion: A Case Report and Literature Review" for BMC Women's Health. The topic was fascinating, and I read the paper with great interest. However, I would like to mention some points: 1. The English language needs revision. 2. The information of the meta-analysis in the introduction can be summarized. Some replication of the symptoms can be found in the introduction and discussion. 3. The authors should elaborate more on the procedure of thrombectomy in the case report section. 4. The authors should mention the dose of heparin. 5. The normal range of laboratory findings should be added. 6. The duration of follow-up and evaluation should be mentioned. 7. The authors mentioned an association between the ChAdOx1 nCoV-19 vaccine and CVST; however, they did not mention the relation with the current case. The authors should mention if the patient received the same vaccine recently. 8. In general, the discussion can be summarized and be more related to the aforementioned patient’s status. 9. The table should be spell-checked.	BMC	12905_2025_3605_ReviewerReport_V2_R5.pdf	{ "criticism": 1, "example": 0, "importance_and_relevance": 1, "materials_and_methods": 5, "praise": 1, "presentation_and_reporting": 11, "results_and_discussion": 3, "suggestion_and_solution": 11, "total": 22 }	{ "criticism": 0.045454545454545456, "example": 0, "importance_and_relevance": 0.045454545454545456, "materials_and_methods": 0.22727272727272727, "praise": 0.045454545454545456, "presentation_and_reporting": 0.5, "results_and_discussion": 0.13636363636363635, "suggestion_and_solution": 0.5 }	1.5	[ { "content": "Please review this paper.", "role": "user" }, { "content": "Title: Cranial Venous Sinus Thrombosis Following Early Spontaneous Abortion: A Case Report\nand Literature Review\nVersion: 2 Date: 12 Jun 2024\nReviewer's report:\nDear Editor,\nThank you for the opportunity to review the article entitled \"Cerebral Venous Sinus Thrombosis\nFollowing Early Spontaneous Abortion: A Case Report and Literature Review\" for BMC\nWomen's Health.\nThe topic was fascinating, and I read the paper with great interest. However, I would like to\nmention some points:\n1. The English language needs revision.\n2. The information of the meta-analysis in the introduction can be summarized. Some replication\nof the symptoms can be found in the introduction and discussion.\n3. The authors should elaborate more on the procedure of thrombectomy in the case report\nsection.\n4. The authors should mention the dose of heparin.\n5. The normal range of laboratory findings should be added.\n6. The duration of follow-up and evaluation should be mentioned.\n7. The authors mentioned an association between the ChAdOx1 nCoV-19 vaccine and CVST;\nhowever, they did not mention the relation with the current case. The authors should mention\nif the patient received the same vaccine recently.\n8. In general, the discussion can be summarized and be more related to the aforementioned\npatient’s status.\n9. The table should be spell-checked.", "role": "assistant" } ]	2,025
Review for 10.1186/s12905-025-03605-6	Reviewed - bmc_womens_health	Title: Cranial Venous Sinus Thrombosis Following Early Spontaneous Abortion: A Case Report and Literature Review Version: 2 Date: 12 Jun 2024 Reviewer: Pavan Kumar Dammalapati Reviewer's report: Good article. Although the CVST is not an uncommon presentation in neurology and late pregnancy, presentation in early pregnancy is relatively rare. Need some corrections highlighted in red. Good luck to the authors.	Title: Cranial Venous Sinus Thrombosis Following Early Spontaneous Abortion: A Case Report and Literature Review Version: 2 Date: 12 Jun 2024 Reviewer: Pavan Kumar Dammalapati Reviewer's report: Good article. Although the CVST is not an uncommon presentation in neurology and late pregnancy, presentation in early pregnancy is relatively rare. Need some corrections highlighted in red. Good luck to the authors.	BMC	12905_2025_3605_ReviewerReport_V2_R11.pdf	{ "criticism": 0, "example": 0, "importance_and_relevance": 0, "materials_and_methods": 0, "praise": 2, "presentation_and_reporting": 1, "results_and_discussion": 0, "suggestion_and_solution": 1, "total": 4 }	{ "criticism": 0, "example": 0, "importance_and_relevance": 0, "materials_and_methods": 0, "praise": 0.5, "presentation_and_reporting": 0.25, "results_and_discussion": 0, "suggestion_and_solution": 0.25 }	1	[ { "content": "Please review this paper.", "role": "user" }, { "content": "Title: Cranial Venous Sinus Thrombosis Following Early Spontaneous Abortion: A Case Report\nand Literature Review\nVersion: 2 Date: 12 Jun 2024\nReviewer: Pavan Kumar Dammalapati\nReviewer's report:\nGood article. Although the CVST is not an uncommon presentation in neurology and late\npregnancy, presentation in early pregnancy is relatively rare. Need some corrections highlighted\nin red. Good luck to the authors.", "role": "assistant" } ]	2,025
Review for 10.1186/s12905-025-03605-6	Reviewed - bmc_womens_health	Title: Cranial Venous Sinus Thrombosis Following Early Spontaneous Abortion: A Case Report and Literature Review Version: 2 Date: 13 Jun 2024 Reviewer: Gowri Dorairajan Reviewer's report: The manuscript is well written. The followings comments may be considered to revise it i. As the woman reported is 38 years 1. it is important to include type of conception and any 2.infertility treatment. 3. Was it a confirmed intrauterine viable pregnancy or an early fetal loss (missed abortion) or a molar pregnancy before she aborted. 4. Any history of fever. 5. Race of the woman for risk assessment 6.Were the peripheral pulses palpable ii. There is a mention of fenestration of the artery in the first imaging. This congenital variation is known to be associated with aneurysm, hemorrhage as well as thrombosis and ischemic stroke. The authors should consider discussing this as well.	Title: Cranial Venous Sinus Thrombosis Following Early Spontaneous Abortion: A Case Report and Literature Review Version: 2 Date: 13 Jun 2024 Reviewer: Gowri Dorairajan Reviewer's report: The manuscript is well written. The followings comments may be considered to revise it i. As the woman reported is 38 years 1. it is important to include type of conception and any 2.infertility treatment. 3. Was it a confirmed intrauterine viable pregnancy or an early fetal loss (missed abortion) or a molar pregnancy before she aborted. 4. Any history of fever. 5. Race of the woman for risk assessment 6.Were the peripheral pulses palpable ii. There is a mention of fenestration of the artery in the first imaging. This congenital variation is known to be associated with aneurysm, hemorrhage as well as thrombosis and ischemic stroke. The authors should consider discussing this as well.	BMC	12905_2025_3605_ReviewerReport_V2_R10.pdf	{ "criticism": 0, "example": 0, "importance_and_relevance": 0, "materials_and_methods": 2, "praise": 1, "presentation_and_reporting": 2, "results_and_discussion": 1, "suggestion_and_solution": 3, "total": 12 }	{ "criticism": 0, "example": 0, "importance_and_relevance": 0, "materials_and_methods": 0.16666666666666666, "praise": 0.08333333333333333, "presentation_and_reporting": 0.16666666666666666, "results_and_discussion": 0.08333333333333333, "suggestion_and_solution": 0.25 }	0.75	[ { "content": "Please review this paper.", "role": "user" }, { "content": "Title: Cranial Venous Sinus Thrombosis Following Early Spontaneous Abortion: A Case Report\nand Literature Review\nVersion: 2 Date: 13 Jun 2024\nReviewer: Gowri Dorairajan\nReviewer's report:\nThe manuscript is well written.\nThe followings comments may be considered to revise it\ni. As the woman reported is 38 years\n1. it is important to include type of conception and any\n2.infertility treatment.\n3. Was it a confirmed intrauterine viable pregnancy or an early fetal loss (missed abortion) or\na molar pregnancy\nbefore she aborted.\n4. Any history of fever.\n5. Race of the woman for risk assessment\n6.Were the peripheral pulses palpable\nii. There is a mention of fenestration of the artery in the first imaging. This congenital variation is\nknown to be associated with aneurysm, hemorrhage as well as thrombosis and ischemic stroke.\nThe authors should consider discussing this as well.", "role": "assistant" } ]	2,025
Review for 10.1186/s12905-025-03605-6	Reviewed - bmc_womens_health	Title: Cranial Venous Sinus Thrombosis Following Early Spontaneous Abortion: A Case Report and Literature Review Version: 2 Date: 14 Jun 2024 Reviewer's report: This case report significantly contributes to medical knowledge by highlighting a rare but serious complication: cerebral venous sinus thrombosis (CVST) following an early spontaneous abortion. The well-organized manuscript provides a thorough description of the patient's case and a comprehensive discussion. However, there are areas where it could be improved. Introduction Rarity Emphasis: Expand the discussion on how rare CVST is following early spontaneous abortion. Cite any available statistics or studies that highlight this rarity. Objectives: State clearly that the objective of this case report is to present a novel occurrence of CVST in this context, and to contribute to the understanding of potential triggers for this condition. Gap in Literature: Briefly summarize what is currently known about CVST risk factors and emphasize that there is limited information on the association with early spontaneous abortion. Case Presentation Differential Diagnosis: Add a paragraph or subsection dedicated to the differential diagnosis. Clearly list the alternative diagnoses that were considered (e.g., migraine, stroke, etc.) and describe the specific findings (clinical or laboratory) that ruled them out in favor of CVST. Discussion Rewrite this section with a more balanced approach. Start by acknowledging that while a causal relationship is possible, it cannot be definitively established based on a single case. Discuss the following: Potential Mechanisms: How could spontaneous abortion theoretically increase the risk of CVST? (e.g., hypercoagulability, hormonal changes) Alternative Risk Factors: Could the patient have had other predisposing factors that were not detected? Coincidence: Could the CVST occurrence have been entirely unrelated to the abortion? Gestational Hyperthyroidism: Dedicate a paragraph to analyzing this condition in more detail. Discuss how it could have potentially contributed to CVST (if at all) based on the current literature. Updated Literature Review: Thoroughly search for and incorporate the latest studies on CVST, especially those published in the last 2-3 years. Focus on any advancements in diagnostic techniques (e.g., new imaging modalities), treatment options (e.g., novel anticoagulants), and insights into risk factors. Conclusion Summary of Findings: Clearly restate the key points of the case: a woman with no other apparent risk factors developed CVST shortly after an early spontaneous abortion. Implications: Emphasize the clinical importance of being aware of this potential association, even if it is rare. Limitations: Explicitly acknowledge the limitations of a single case report in establishing causality. Call for Research: Conclude by advocating for prospective studies to investigate the link between early spontaneous abortion and CVST, as well as research on other potential risk factors. Additional Revisions Table: Consider adding a table summarizing the key features of other reported cases of CVST in pregnancy (if any exist), to provide further context for your case. Language and Formatting: Thoroughly proofread for any grammatical errors or inconsistencies in formatting. Thank you .	Title: Cranial Venous Sinus Thrombosis Following Early Spontaneous Abortion: A Case Report and Literature Review Version: 2 Date: 14 Jun 2024 Reviewer's report: This case report significantly contributes to medical knowledge by highlighting a rare but serious complication: cerebral venous sinus thrombosis (CVST) following an early spontaneous abortion. The well-organized manuscript provides a thorough description of the patient's case and a comprehensive discussion. However, there are areas where it could be improved. Introduction Rarity Emphasis: Expand the discussion on how rare CVST is following early spontaneous abortion. Cite any available statistics or studies that highlight this rarity. Objectives: State clearly that the objective of this case report is to present a novel occurrence of CVST in this context, and to contribute to the understanding of potential triggers for this condition. Gap in Literature: Briefly summarize what is currently known about CVST risk factors and emphasize that there is limited information on the association with early spontaneous abortion. Case Presentation Differential Diagnosis: Add a paragraph or subsection dedicated to the differential diagnosis. Clearly list the alternative diagnoses that were considered (e.g., migraine, stroke, etc.) and describe the specific findings (clinical or laboratory) that ruled them out in favor of CVST. Discussion Rewrite this section with a more balanced approach. Start by acknowledging that while a causal relationship is possible, it cannot be definitively established based on a single case. Discuss the following: Potential Mechanisms: How could spontaneous abortion theoretically increase the risk of CVST? (e.g., hypercoagulability, hormonal changes) Alternative Risk Factors: Could the patient have had other predisposing factors that were not detected? Coincidence: Could the CVST occurrence have been entirely unrelated to the abortion? Gestational Hyperthyroidism: Dedicate a paragraph to analyzing this condition in more detail. Discuss how it could have potentially contributed to CVST (if at all) based on the current literature. Updated Literature Review: Thoroughly search for and incorporate the latest studies on CVST, especially those published in the last 2-3 years. Focus on any advancements in diagnostic techniques (e.g., new imaging modalities), treatment options (e.g., novel anticoagulants), and insights into risk factors. Conclusion Summary of Findings: Clearly restate the key points of the case: a woman with no other apparent risk factors developed CVST shortly after an early spontaneous abortion. Implications: Emphasize the clinical importance of being aware of this potential association, even if it is rare. Limitations: Explicitly acknowledge the limitations of a single case report in establishing causality. Call for Research: Conclude by advocating for prospective studies to investigate the link between early spontaneous abortion and CVST, as well as research on other potential risk factors. Additional Revisions Table: Consider adding a table summarizing the key features of other reported cases of CVST in pregnancy (if any exist), to provide further context for your case. Language and Formatting: Thoroughly proofread for any grammatical errors or inconsistencies in formatting. Thank you .	BMC	12905_2025_3605_ReviewerReport_V2_R8.pdf	{ "criticism": 0, "example": 0, "importance_and_relevance": 5, "materials_and_methods": 6, "praise": 2, "presentation_and_reporting": 9, "results_and_discussion": 7, "suggestion_and_solution": 17, "total": 26 }	{ "criticism": 0, "example": 0, "importance_and_relevance": 0.19230769230769232, "materials_and_methods": 0.23076923076923078, "praise": 0.07692307692307693, "presentation_and_reporting": 0.34615384615384615, "results_and_discussion": 0.2692307692307692, "suggestion_and_solution": 0.6538461538461539 }	1.769231	[ { "content": "Please review this paper.", "role": "user" }, { "content": "Title: Cranial Venous Sinus Thrombosis Following Early Spontaneous Abortion: A Case Report\nand Literature Review\nVersion: 2 Date: 14 Jun 2024\nReviewer's report:\nThis case report significantly contributes to medical knowledge by highlighting a rare but\nserious complication: cerebral venous sinus thrombosis (CVST) following an early spontaneous\nabortion. The well-organized manuscript provides a thorough description of the patient's case\nand a comprehensive discussion. However, there are areas where it could be improved.\nIntroduction\nRarity Emphasis: Expand the discussion on how rare CVST is following early spontaneous\nabortion. Cite any available statistics or studies that highlight this rarity.\nObjectives: State clearly that the objective of this case report is to present a novel occurrence\nof CVST in this context, and to contribute to the understanding of potential triggers for this\ncondition.\nGap in Literature: Briefly summarize what is currently known about CVST risk factors and\nemphasize that there is limited information on the association with early spontaneous abortion.\nCase Presentation\nDifferential Diagnosis: Add a paragraph or subsection dedicated to the differential diagnosis.\nClearly list the alternative diagnoses that were considered (e.g., migraine, stroke, etc.) and\ndescribe the specific findings (clinical or laboratory) that ruled them out in favor of CVST.\nDiscussion\nRewrite this section with a more balanced approach. Start by acknowledging that while a causal\nrelationship is possible, it cannot be definitively established based on a single case. Discuss the\nfollowing:\nPotential Mechanisms: How could spontaneous abortion theoretically increase the risk of\nCVST? (e.g., hypercoagulability, hormonal changes)\nAlternative Risk Factors: Could the patient have had other predisposing factors that were not\ndetected?\nCoincidence: Could the CVST occurrence have been entirely unrelated to the abortion?\nGestational Hyperthyroidism: Dedicate a paragraph to analyzing this condition in more detail.\nDiscuss how it could have potentially contributed to CVST (if at all) based on the current\nliterature.\nUpdated Literature Review:\nThoroughly search for and incorporate the latest studies on CVST, especially those published\nin the last 2-3 years. Focus on any advancements in diagnostic techniques (e.g., new imaging\nmodalities), treatment options (e.g., novel anticoagulants), and insights into risk factors.\nConclusion\nSummary of Findings:\nClearly restate the key points of the case: a woman with no other apparent risk factors developed\nCVST shortly after an early spontaneous abortion.\nImplications: Emphasize the clinical importance of being aware of this potential association,\neven if it is rare.\nLimitations: Explicitly acknowledge the limitations of a single case report in establishing\ncausality.\nCall for Research: Conclude by advocating for prospective studies to investigate the link between\nearly spontaneous abortion and CVST, as well as research on other potential risk factors.\nAdditional Revisions\nTable: Consider adding a table summarizing the key features of other reported cases of CVST\nin pregnancy (if any exist), to provide further context for your case.\nLanguage and Formatting: Thoroughly proofread for any grammatical errors or inconsistencies\nin formatting.\nThank you .", "role": "assistant" } ]	2,025
Review for 10.1186/s12905-025-03605-6	Reviewed - bmc_womens_health	Title: Cranial Venous Sinus Thrombosis Following Early Spontaneous Abortion: A Case Report and Literature Review Version: 2 Date: 17 Jun 2024 Reviewer's report: Abstract: Give precise details about the case. Shorten the fisrt 2 sentences and the beginning of the 3rd sentence. Background p2, L39: cite articles about radiological diagnosis of CVT: Idbaih; Boukobza (cortical CVT; SAH and CVT) Case p3: HGC decrease: what rate? Shorten when examination is unremarkable. L60: what is a "minor SAH"? CT angiography was obtained: why not a venous CTA? Hemo in the right temoralL: be more precise; size of the hemorrhage. Why MRI "under local anesthesia": precise, explain. MRI.... angiograhy: write the usual: MRA heparin therapy: what dosage? What treatment after thrombectomy? Follow-up? clinical delay? Discussion p4, l83: the abbreviation "CVST" was previously given. p5, L90: and cavernous sinus thrombosis? l94: during Covid? l 96: most cv occlusions progress to... give the %. Not in "most" l 100-104: lacks precision p7: L36: "one patient, misdiagnosed": off topic - l52: these signs/symptoms are common in CVT and are not characteristic of CVT during early pregnancy p9: - l 163: refer to major articles: Idbaih, M Boukobza, Lafitte - l 166: did not concern the reported case. Better to discuss about the reported case. It is not the purpose of this case to take stock of the CVT. Focus on the presented case Figure 1: the topograohy of the hematoma evoke a Labbé vein thrombosis, perhaps associated with lateral sinus thrombosis: discuss in the text, cite: Boukobza, Labbé vein thrombosis, underline in the legend.	Title: Cranial Venous Sinus Thrombosis Following Early Spontaneous Abortion: A Case Report and Literature Review Version: 2 Date: 17 Jun 2024 Reviewer's report: Abstract: Give precise details about the case. Shorten the fisrt 2 sentences and the beginning of the 3rd sentence. Background p2, L39: cite articles about radiological diagnosis of CVT: Idbaih; Boukobza (cortical CVT; SAH and CVT) Case p3: HGC decrease: what rate? Shorten when examination is unremarkable. L60: what is a "minor SAH"? CT angiography was obtained: why not a venous CTA? Hemo in the right temoralL: be more precise; size of the hemorrhage. Why MRI "under local anesthesia": precise, explain. MRI.... angiograhy: write the usual: MRA heparin therapy: what dosage? What treatment after thrombectomy? Follow-up? clinical delay? Discussion p4, l83: the abbreviation "CVST" was previously given. p5, L90: and cavernous sinus thrombosis? l94: during Covid? l 96: most cv occlusions progress to... give the %. Not in "most" l 100-104: lacks precision p7: L36: "one patient, misdiagnosed": off topic - l52: these signs/symptoms are common in CVT and are not characteristic of CVT during early pregnancy p9: - l 163: refer to major articles: Idbaih, M Boukobza, Lafitte - l 166: did not concern the reported case. Better to discuss about the reported case. It is not the purpose of this case to take stock of the CVT. Focus on the presented case Figure 1: the topograohy of the hematoma evoke a Labbé vein thrombosis, perhaps associated with lateral sinus thrombosis: discuss in the text, cite: Boukobza, Labbé vein thrombosis, underline in the legend.	BMC	12905_2025_3605_ReviewerReport_V2_R4.pdf	{ "criticism": 1, "example": 9, "importance_and_relevance": 0, "materials_and_methods": 4, "praise": 0, "presentation_and_reporting": 8, "results_and_discussion": 0, "suggestion_and_solution": 8, "total": 20 }	{ "criticism": 0.05, "example": 0.45, "importance_and_relevance": 0, "materials_and_methods": 0.2, "praise": 0, "presentation_and_reporting": 0.4, "results_and_discussion": 0, "suggestion_and_solution": 0.4 }	1.5	[ { "content": "Please review this paper.", "role": "user" }, { "content": "Title: Cranial Venous Sinus Thrombosis Following Early Spontaneous Abortion: A Case Report\nand Literature Review\nVersion: 2 Date: 17 Jun 2024\nReviewer's report:\nAbstract:\nGive precise details about the case. Shorten the fisrt 2 sentences and the beginning of the 3rd\nsentence.\nBackground\np2, L39: cite articles about radiological diagnosis of CVT: Idbaih; Boukobza (cortical CVT;\nSAH and CVT)\nCase\np3: HGC decrease: what rate?\nShorten when examination is unremarkable.\nL60: what is a \"minor SAH\"?\nCT angiography was obtained: why not a venous CTA?\nHemo in the right temoralL: be more precise; size of the hemorrhage.\nWhy MRI \"under local anesthesia\": precise, explain.\nMRI.... angiograhy: write the usual: MRA\nheparin therapy: what dosage?\nWhat treatment after thrombectomy?\nFollow-up? clinical delay?\nDiscussion\np4, l83: the abbreviation \"CVST\" was previously given.\np5, L90: and cavernous sinus thrombosis?\nl94: during Covid?\nl 96: most cv occlusions progress to... give the %. Not in \"most\"\nl 100-104: lacks precision\np7: L36: \"one patient, misdiagnosed\": off topic\n- l52: these signs/symptoms are common in CVT and are not characteristic of CVT during early\npregnancy\np9:\n- l 163: refer to major articles: Idbaih, M Boukobza, Lafitte\n- l 166: did not concern the reported case. Better to discuss about the reported case.\nIt is not the purpose of this case to take stock of the CVT. Focus on the presented case\nFigure 1: the topograohy of the hematoma evoke a Labbé vein thrombosis, perhaps associated\nwith lateral sinus thrombosis: discuss in the text, cite: Boukobza, Labbé vein thrombosis,\nunderline in the legend.", "role": "assistant" } ]	2,025
Review for 10.1186/s12905-025-03605-6	Reviewed - bmc_womens_health	Title: Cranial Venous Sinus Thrombosis Following Early Spontaneous Abortion: A Case Report and Literature Review Version: 2 Date: 19 Jun 2024 Reviewer's report: well managed case. ideal time to rule out Antiphospholipid antibody syndrome and other thrombophilia is minimum 6 weeks postpartum or postabortal .i wonder if it was known before the index pregnancy.	Title: Cranial Venous Sinus Thrombosis Following Early Spontaneous Abortion: A Case Report and Literature Review Version: 2 Date: 19 Jun 2024 Reviewer's report: well managed case. ideal time to rule out Antiphospholipid antibody syndrome and other thrombophilia is minimum 6 weeks postpartum or postabortal .i wonder if it was known before the index pregnancy.	BMC	12905_2025_3605_ReviewerReport_V2_R12.pdf	{ "criticism": 0, "example": 0, "importance_and_relevance": 0, "materials_and_methods": 0, "praise": 1, "presentation_and_reporting": 0, "results_and_discussion": 0, "suggestion_and_solution": 0, "total": 2 }	{ "criticism": 0, "example": 0, "importance_and_relevance": 0, "materials_and_methods": 0, "praise": 0.5, "presentation_and_reporting": 0, "results_and_discussion": 0, "suggestion_and_solution": 0 }	0.5	[ { "content": "Please review this paper.", "role": "user" }, { "content": "Title: Cranial Venous Sinus Thrombosis Following Early Spontaneous Abortion: A Case Report\nand Literature Review\nVersion: 2 Date: 19 Jun 2024\nReviewer's report:\nwell managed case. ideal time to rule out Antiphospholipid antibody syndrome and other\nthrombophilia is minimum 6 weeks postpartum or postabortal .i wonder if it was known before\nthe index pregnancy.", "role": "assistant" } ]	2,025

End of preview. Expand in Data Studio

BMC Women's Health Peer Reviews

This dataset contains peer reviews from BMC, standardized to match the format of the pawin205/PeerRT dataset.

Dataset Structure

Each record contains the following attributes:

relative_rank: Default value (0).
win_prob: Default value (0.0).
title: Title of the paper.
abstract: Abstract of the paper.
full_text: Full text of the paper (or review text if unavailable).
review: The peer review text.
source: Source of the data ('BMC').
review_src: Original filename of the review.
criteria_count: Dictionary containing counts of specific criteria in the review (e.g., criticism, praise).
dimension_scores: Dictionary containing scores for various dimensions.
overall_score: Computed overall score (reward value).
thinking_trace: Placeholder (empty).
prompt: Placeholder (empty).
prompt_length: Placeholder (0).
conversations: List of dictionaries representing the conversation (User/Assistant format).
year: Year of publication (if available).

Usage

from datasets import load_dataset

dataset = load_dataset("JerMa88/BMC_Womens_Health_Peer_Reviews")
print(dataset['train'][0])

Downloads last month: 29

: (See dataset viewer)

Size of downloaded dataset files:

51.5 MB

Size of the auto-converted Parquet files:

51.5 MB

Number of rows:

17,379